Fisiopatoligia de las tormentas electricas en el encefalo del paciente con una lesion cerebral aguda. Resultados preliminares de un estudio piloto

J Sahuquillo; M Sueiras; B Garcia-Lopez; MA Merino; T Martinez-Valverde; F Martinez-Ricarte; R Torne; E Cobos; MA Poca; Martin Ejler Fabricius

Fisiopatoligia de las tormentas electricas en el encefalo del paciente con una lesion cerebral aguda. Resultados preliminares de un estudio piloto

J Sahuquillo, M Sueiras, B Garcia-Lopez , MA Merino, T Martinez-Valverde, F Martinez-Ricarte , R Torne, E Cobos, MA Poca, Martin Ejler Fabricius

Afdeling for Hjerne- og Nerveundersøgelser NEU

Abstract

The phenomena of cortical spreading depolarization (CSD and CSD-like phenomena) are cellular depolarization waves involved in the progression of lesions in patients with stroke and traumatic brain injury (TBI). Which are detected by an electrocorticographic (ECoG) recording. Experimentally, CSD induces cerebral hypoxia and increases the permeability of the blood-brain barrier.
Objectives: To determine the frequency and duration of CSD episodes in patients with TBI and malignant middle cerebral artery infarction (MMCAI) requiring craniectomy.
Material and methods: 20 patients were included. A strip of 6 electrodes was placed in the perilesional cortex. Analysis of the number and duration of CSD episodes in the ECoG recording was performed.
Results: In four, of the eight ECoG recordings that was fully analyzed, CSD or CSD-like phenomena were identified with a variable frequency and duration.
Conclusions: Episodes of CSD and CSD-like phenomena are frequently detected in patients with MMCAI and TBI.

Bidragets oversatte titel	Pathophysiology of electrical storms in the brain of patients with acute brain injury. Preliminary results of a pilot study
Originalsprog	Spansk
Tidsskrift	Trauma
Vol/bind	22
Udgave nummer	4
Sider (fra-til)	272-280
Antal sider	9
ISSN	1888-6116
Status	Udgivet - 2011

Citationsformater

@article{57e4b7bb8bcc4b229220f43831adc4c9,

title = "Fisiopatoligia de las tormentas electricas en el encefalo del paciente con una lesion cerebral aguda. Resultados preliminares de un estudio piloto",

abstract = "The phenomena of cortical spreading depolarization (CSD and CSD-like phenomena) are cellular depolarization waves involved in the progression of lesions in patients with stroke and traumatic brain injury (TBI). Which are detected by an electrocorticographic (ECoG) recording. Experimentally, CSD induces cerebral hypoxia and increases the permeability of the blood-brain barrier. Objectives: To determine the frequency and duration of CSD episodes in patients with TBI and malignant middle cerebral artery infarction (MMCAI) requiring craniectomy. Material and methods: 20 patients were included. A strip of 6 electrodes was placed in the perilesional cortex. Analysis of the number and duration of CSD episodes in the ECoG recording was performed. Results: In four, of the eight ECoG recordings that was fully analyzed, CSD or CSD-like phenomena were identified with a variable frequency and duration. Conclusions: Episodes of CSD and CSD-like phenomena are frequently detected in patients with MMCAI and TBI.",

author = "J Sahuquillo and M Sueiras and B Garcia-Lopez and MA Merino and T Martinez-Valverde and F Martinez-Ricarte and R Torne and E Cobos and MA Poca and Fabricius, {Martin Ejler}",

year = "2011",

language = "Spansk",

volume = "22",

pages = "272--280",

journal = "Trauma",

issn = "1888-6116",

publisher = "Fundacion Mapfre Medicina",

number = "4",

}

TY - JOUR

T1 - Fisiopatoligia de las tormentas electricas en el encefalo del paciente con una lesion cerebral aguda. Resultados preliminares de un estudio piloto

AU - Sahuquillo, J

AU - Sueiras, M

AU - Garcia-Lopez , B

AU - Merino, MA

AU - Martinez-Valverde, T

AU - Martinez-Ricarte , F

AU - Torne, R

AU - Cobos, E

AU - Poca, MA

AU - Fabricius, Martin Ejler

PY - 2011

Y1 - 2011

N2 - The phenomena of cortical spreading depolarization (CSD and CSD-like phenomena) are cellular depolarization waves involved in the progression of lesions in patients with stroke and traumatic brain injury (TBI). Which are detected by an electrocorticographic (ECoG) recording. Experimentally, CSD induces cerebral hypoxia and increases the permeability of the blood-brain barrier. Objectives: To determine the frequency and duration of CSD episodes in patients with TBI and malignant middle cerebral artery infarction (MMCAI) requiring craniectomy. Material and methods: 20 patients were included. A strip of 6 electrodes was placed in the perilesional cortex. Analysis of the number and duration of CSD episodes in the ECoG recording was performed. Results: In four, of the eight ECoG recordings that was fully analyzed, CSD or CSD-like phenomena were identified with a variable frequency and duration. Conclusions: Episodes of CSD and CSD-like phenomena are frequently detected in patients with MMCAI and TBI.

AB - The phenomena of cortical spreading depolarization (CSD and CSD-like phenomena) are cellular depolarization waves involved in the progression of lesions in patients with stroke and traumatic brain injury (TBI). Which are detected by an electrocorticographic (ECoG) recording. Experimentally, CSD induces cerebral hypoxia and increases the permeability of the blood-brain barrier. Objectives: To determine the frequency and duration of CSD episodes in patients with TBI and malignant middle cerebral artery infarction (MMCAI) requiring craniectomy. Material and methods: 20 patients were included. A strip of 6 electrodes was placed in the perilesional cortex. Analysis of the number and duration of CSD episodes in the ECoG recording was performed. Results: In four, of the eight ECoG recordings that was fully analyzed, CSD or CSD-like phenomena were identified with a variable frequency and duration. Conclusions: Episodes of CSD and CSD-like phenomena are frequently detected in patients with MMCAI and TBI.

M3 - Tidsskriftartikel

SN - 1888-6116

VL - 22

SP - 272

EP - 280

JO - Trauma

JF - Trauma

IS - 4

ER -

Fisiopatoligia de las tormentas electricas en el encefalo del paciente con una lesion cerebral aguda. Resultados preliminares de un estudio piloto

Abstract

Fingeraftryk

Citationsformater