Fibulin-1 is a marker for arterial extracellular matrix alterations in type 2 diabetes

Claudia Cangemi; Vibe Skov; Michael Kjaer Poulsen; Jonas Amstrup Funder; Waleed O Twal; Mari-Anne Gall; Vibeke E. Hjortdal; Marie Louise Jespersen; Torben A Kruse; Jan Aagard; Hans-Henrik Parving; Steen Knudsen; Poul-Flemming Høilund-Carlsen; Peter Rossing; Jan Erik Henriksen; William Scott Argraves; Lars Melholt Rasmussen

doi:10.1373/clinchem.2011.162966

Fibulin-1 is a marker for arterial extracellular matrix alterations in type 2 diabetes

Claudia Cangemi, Vibe Skov, Michael Kjaer Poulsen, Jonas Amstrup Funder, Waleed O Twal, Mari-Anne Gall, Vibeke E. Hjortdal, Marie Louise Jespersen, Torben A Kruse, Jan Aagard, Hans-Henrik Parving, Steen Knudsen, Poul-Flemming Høilund-Carlsen, Peter Rossing, Jan Erik Henriksen, William Scott Argraves, Lars Melholt Rasmussen

68 Citationer (Scopus)

Abstract

Extracellular matrix alterations are important elements in the arterial changes seen in diabetes, being associated with increased vascular stiffness and the development of cardiovascular diseases. However, no biomarkers for diabetes-related arterial changes have been defined.

Originalsprog	Engelsk
Tidsskrift	Clinical Chemistry (Washington, DC)
Vol/bind	57
Udgave nummer	11
Sider (fra-til)	1556-65
Antal sider	10
ISSN	0009-9147
DOI	https://doi.org/10.1373/clinchem.2011.162966
Status	Udgivet - 2011

Adgang til dokumentet

10.1373/clinchem.2011.162966

Citationsformater

Cangemi, C., Skov, V., Poulsen, M. K., Funder, J. A., Twal, W. O., Gall, M.-A., Hjortdal, V. E., Jespersen, M. L., Kruse, T. A., Aagard, J., Parving, H.-H., Knudsen, S., Høilund-Carlsen, P.-F., Rossing, P., Henriksen, J. E., Argraves, W. S., & Rasmussen, L. M. (2011). Fibulin-1 is a marker for arterial extracellular matrix alterations in type 2 diabetes. Clinical Chemistry (Washington, DC), 57(11), 1556-65. https://doi.org/10.1373/clinchem.2011.162966

Cangemi, C, Skov, V, Poulsen, MK, Funder, JA, Twal, WO, Gall, M-A, Hjortdal, VE, Jespersen, ML, Kruse, TA, Aagard, J, Parving, H-H, Knudsen, S, Høilund-Carlsen, P-F, Rossing, P, Henriksen, JE, Argraves, WS & Rasmussen, LM 2011, 'Fibulin-1 is a marker for arterial extracellular matrix alterations in type 2 diabetes', Clinical Chemistry (Washington, DC), bind 57, nr. 11, s. 1556-65. https://doi.org/10.1373/clinchem.2011.162966

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title = "Fibulin-1 is a marker for arterial extracellular matrix alterations in type 2 diabetes",

abstract = "Extracellular matrix alterations are important elements in the arterial changes seen in diabetes, being associated with increased vascular stiffness and the development of cardiovascular diseases. However, no biomarkers for diabetes-related arterial changes have been defined.",

keywords = "Aged, Biological Markers, Calcium-Binding Proteins, Cardiovascular Diseases, Carotid Intima-Media Thickness, Case-Control Studies, Diabetes Mellitus, Type 2, Extracellular Matrix, Extracellular Matrix Proteins, Female, Follow-Up Studies, Humans, Immunoassay, Immunohistochemistry, Male, Mammary Arteries, Middle Aged, Oligonucleotide Array Sequence Analysis, Predictive Value of Tests, Prospective Studies, Real-Time Polymerase Chain Reaction",

author = "Claudia Cangemi and Vibe Skov and Poulsen, {Michael Kjaer} and Funder, {Jonas Amstrup} and Twal, {Waleed O} and Mari-Anne Gall and Hjortdal, {Vibeke E.} and Jespersen, {Marie Louise} and Kruse, {Torben A} and Jan Aagard and Hans-Henrik Parving and Steen Knudsen and Poul-Flemming H{\o}ilund-Carlsen and Peter Rossing and Henriksen, {Jan Erik} and Argraves, {William Scott} and Rasmussen, {Lars Melholt}",

year = "2011",

doi = "10.1373/clinchem.2011.162966",

language = "English",

volume = "57",

pages = "1556--65",

journal = "Clinical Chemistry (Washington, DC)",

issn = "0009-9147",

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T1 - Fibulin-1 is a marker for arterial extracellular matrix alterations in type 2 diabetes

AU - Cangemi, Claudia

AU - Skov, Vibe

AU - Poulsen, Michael Kjaer

AU - Funder, Jonas Amstrup

AU - Twal, Waleed O

AU - Gall, Mari-Anne

AU - Hjortdal, Vibeke E.

AU - Jespersen, Marie Louise

AU - Kruse, Torben A

AU - Aagard, Jan

AU - Parving, Hans-Henrik

AU - Knudsen, Steen

AU - Høilund-Carlsen, Poul-Flemming

AU - Rossing, Peter

AU - Henriksen, Jan Erik

AU - Argraves, William Scott

AU - Rasmussen, Lars Melholt

PY - 2011

Y1 - 2011

N2 - Extracellular matrix alterations are important elements in the arterial changes seen in diabetes, being associated with increased vascular stiffness and the development of cardiovascular diseases. However, no biomarkers for diabetes-related arterial changes have been defined.

AB - Extracellular matrix alterations are important elements in the arterial changes seen in diabetes, being associated with increased vascular stiffness and the development of cardiovascular diseases. However, no biomarkers for diabetes-related arterial changes have been defined.

KW - Aged

KW - Biological Markers

KW - Calcium-Binding Proteins

KW - Cardiovascular Diseases

KW - Carotid Intima-Media Thickness

KW - Case-Control Studies

KW - Diabetes Mellitus, Type 2

KW - Extracellular Matrix

KW - Extracellular Matrix Proteins

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Immunoassay

KW - Immunohistochemistry

KW - Male

KW - Mammary Arteries

KW - Middle Aged

KW - Oligonucleotide Array Sequence Analysis

KW - Predictive Value of Tests

KW - Prospective Studies

KW - Real-Time Polymerase Chain Reaction

U2 - 10.1373/clinchem.2011.162966

DO - 10.1373/clinchem.2011.162966

M3 - Journal article

C2 - 21926180

SN - 0009-9147

VL - 57

SP - 1556

EP - 1565

JO - Clinical Chemistry (Washington, DC)

JF - Clinical Chemistry (Washington, DC)

IS - 11

ER -

Fibulin-1 is a marker for arterial extracellular matrix alterations in type 2 diabetes

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