Fedmens genetik

Søren M Echwald, Philip Just Larsen, Oluf Borbye Pedersen, Thorkild I A Sørensen

    1 Citationer (Scopus)

    Abstract

    Although environmental factors clearly play a role, studies of twins and adoptees show that obesity is a familial trait which to a large degree can be ascribed to genetic factors. According to evolutionary models, obesity-causing variants may originally have had an evolutionary benefit, whereas in a modern environment they pose a risk. Despite a clear genetic cause, the molecular genetic variations underlying common forms of obesity are not clear. Out of many hundred candidates, only a few hold up, and only variations in the MC4R gene have been found with a prevalence which may lead to common forms of obesity.

    Bidragets oversatte titelThe genetics of obesity
    OriginalsprogDansk
    TidsskriftUgeskrift for Laeger
    Vol/bind168
    Udgave nummer2
    Sider (fra-til)150-2
    Antal sider3
    ISSN0041-5782
    StatusUdgivet - 9 jan. 2006

    Emneord

    • Genetic Predisposition to Disease
    • Humans
    • Obesity

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