Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Feasibility of a novel liquid fiducial marker for use in image guided radiotherapy of oesophageal cancer

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Evaluation of uterine ultrasound imaging in cervical radiotherapy; a comparison of autoscan and conventional probe

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Reproducibility of (18)F-FDG PET uptake measurements in head and neck squamous cell carcinoma on both PET/CT and PET/MR

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. PET/CT-guided treatment planning for paediatric cancer patients: a simulation study of proton and conventional photon therapy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Biological optimization for mediastinal lymphoma radiotherapy - a preliminary study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Early Appearance of Coronavirus Disease 2019 Associated Pulmonary Infiltrates During Daily Radiotherapy Imaging for Lung Cancer

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. ILROG emergency guidelines for radiation therapy of hematological malignancies during the COVID-19 pandemic

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVE:: To evaluate the feasibility of a new liquid fiducial marker for use in image-guided radiotherapy for oesophageal cancer.

METHODS:: Liquid fiducial markers were implanted in patients with metastatic or inoperable locally advanced oesophageal or gastro-oesophageal junction cancer receiving radiotherapy. Markers were implanted using a conventional gastroscope equipped with a 22 G Wang needle. Marker visibility was evaluated on fluoroscopy, CT, MRI and cone beam CT scans.

RESULTS:: Liquid markers (n = 16) were injected in four patients. No Grade 2 or worse adverse events were observed in relation to the implantation procedure, during treatment or in the follow-up period. 12/16 (75%) markers were available at the planning CT-scan and throughout the treatment- and follow-up period. The implanted markers were adequately visible in CT and cone beam CT but were difficult to distinguish in fluoroscopy and MRI without information from the corresponding CT image.

CONCLUSION:: Liquid fiducial marker placement in the oesophagus proved safe and clinically feasible.

ADVANCES IN KNOWLEDGE:: This paper presents the first clinical use of a new liquid fiducial marker in patients with oesophageal cancer and demonstrates that marker implantation using standard gastroscopic equipment and subsequent use in three-dimensional image-guided radiation therapy is safe and clinically feasible.

OriginalsprogEngelsk
TidsskriftThe British journal of radiology
Vol/bind91
Udgave nummer1092
Sider (fra-til)20180236
ISSN0007-1285
DOI
StatusUdgivet - 2018

ID: 56091620