Abstract
This is a case report of an 83-year-old man in warfarin treatment with stable international normalised ratio (INR) after aortic valve replacement and atrial fibrillation. Due to back pain he took paracetamol (acetaminophen) 4 g/day, morphine 30 mg/day and diclofenac as rescue medication for two weeks. After 14 days of treatment he was admitted to a hospital with acute neurological deficits, and a blood sample showed INR levels above 10. A CT-scan of the brain showed an intracerebral haemorrhage. The patient died eight days after admission. Mechanisms of the possible interaction between paracetamol and warfarin are discussed.
Bidragets oversatte titel | Fatal intracerebral haemorrhage possibly caused by interaction between paracetamol and warfarin |
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Originalsprog | Dansk |
Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 177 |
Udgave nummer | 23 |
Sider (fra-til) | V12140685 |
ISSN | 0041-5782 |
Status | Udgivet - 1 jun. 2015 |