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Familial associations in hair cortisol concentration: A cross-sectional analysis based on the Healthy Start study

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@article{67eba5434b7747d291d9b4842d6f4f8b,
title = "Familial associations in hair cortisol concentration: A cross-sectional analysis based on the Healthy Start study",
abstract = "A few studies have shown a direct association between maternal and child hair cortisol concentrations (HCC), but the potential correlations within paternal-child and maternal-paternal dyads are not clear from the current evidence. Thus, we aimed to thoroughly examine associations between family members HCC. We conducted a cross-sectional study based on 159 children and their parents (159 mothers and 159 fathers) participating in the Danish Healthy Start Study. Information was available on HCC from both children, mothers and fathers, as well as on several sociodemographic factors. First, Pearson's correlation coefficients were applied to assess crude correlations between family members' HCC. Secondly, analysis of covariance, adjusted for covariates, was applied to estimate child mean HCC in quartiles of maternal and paternal HCC, and mean paternal HCC in quartiles of maternal HCC. Our results showed direct associations between HCC of all family members. We found statistically robust correlations between maternal and child HCC (r = 0.33; P < 0.001), paternal and child HCC (r = 0.37; P < 0.001) and between maternal and paternal HCC (r = 0.31; P < 0.001). Similar results were found when adjusting for covariates in analyses of covariance. Our data provides evidence of associations between family members' HCC. However, we were unable to determine the extent to which these associations were due to shared genetics, assortative mating or environmental factors.",
keywords = "Chronic stress, Cortisol, Hair cortisol, Stress",
author = "Simon Dauegaard and Olsen, {Nanna J} and Heitmann, {Berit L} and Larsen, {Sofus C}",
note = "Copyright {\textcopyright} 2020 Elsevier Ltd. All rights reserved.",
year = "2020",
month = nov,
doi = "10.1016/j.psyneuen.2020.104836",
language = "English",
volume = "121",
pages = "104836",
journal = "Psychoneuroendocrinology",
issn = "0306-4530",
publisher = "Pergamon",

}

RIS

TY - JOUR

T1 - Familial associations in hair cortisol concentration

T2 - A cross-sectional analysis based on the Healthy Start study

AU - Dauegaard, Simon

AU - Olsen, Nanna J

AU - Heitmann, Berit L

AU - Larsen, Sofus C

N1 - Copyright © 2020 Elsevier Ltd. All rights reserved.

PY - 2020/11

Y1 - 2020/11

N2 - A few studies have shown a direct association between maternal and child hair cortisol concentrations (HCC), but the potential correlations within paternal-child and maternal-paternal dyads are not clear from the current evidence. Thus, we aimed to thoroughly examine associations between family members HCC. We conducted a cross-sectional study based on 159 children and their parents (159 mothers and 159 fathers) participating in the Danish Healthy Start Study. Information was available on HCC from both children, mothers and fathers, as well as on several sociodemographic factors. First, Pearson's correlation coefficients were applied to assess crude correlations between family members' HCC. Secondly, analysis of covariance, adjusted for covariates, was applied to estimate child mean HCC in quartiles of maternal and paternal HCC, and mean paternal HCC in quartiles of maternal HCC. Our results showed direct associations between HCC of all family members. We found statistically robust correlations between maternal and child HCC (r = 0.33; P < 0.001), paternal and child HCC (r = 0.37; P < 0.001) and between maternal and paternal HCC (r = 0.31; P < 0.001). Similar results were found when adjusting for covariates in analyses of covariance. Our data provides evidence of associations between family members' HCC. However, we were unable to determine the extent to which these associations were due to shared genetics, assortative mating or environmental factors.

AB - A few studies have shown a direct association between maternal and child hair cortisol concentrations (HCC), but the potential correlations within paternal-child and maternal-paternal dyads are not clear from the current evidence. Thus, we aimed to thoroughly examine associations between family members HCC. We conducted a cross-sectional study based on 159 children and their parents (159 mothers and 159 fathers) participating in the Danish Healthy Start Study. Information was available on HCC from both children, mothers and fathers, as well as on several sociodemographic factors. First, Pearson's correlation coefficients were applied to assess crude correlations between family members' HCC. Secondly, analysis of covariance, adjusted for covariates, was applied to estimate child mean HCC in quartiles of maternal and paternal HCC, and mean paternal HCC in quartiles of maternal HCC. Our results showed direct associations between HCC of all family members. We found statistically robust correlations between maternal and child HCC (r = 0.33; P < 0.001), paternal and child HCC (r = 0.37; P < 0.001) and between maternal and paternal HCC (r = 0.31; P < 0.001). Similar results were found when adjusting for covariates in analyses of covariance. Our data provides evidence of associations between family members' HCC. However, we were unable to determine the extent to which these associations were due to shared genetics, assortative mating or environmental factors.

KW - Chronic stress

KW - Cortisol

KW - Hair cortisol

KW - Stress

UR - http://www.scopus.com/inward/record.url?scp=85089798433&partnerID=8YFLogxK

U2 - 10.1016/j.psyneuen.2020.104836

DO - 10.1016/j.psyneuen.2020.104836

M3 - Journal article

C2 - 32858307

VL - 121

SP - 104836

JO - Psychoneuroendocrinology

JF - Psychoneuroendocrinology

SN - 0306-4530

M1 - 104836

ER -

ID: 61192920