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Eye gaze and facial displays of emotion during emotional film clips in remitted patients with bipolar disorder

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@article{f8885195303041778530d78c6ad67554,
title = "Eye gaze and facial displays of emotion during emotional film clips in remitted patients with bipolar disorder",
abstract = "BACKGROUND.: Aberrant emotional reactivity is a putative endophenotype for bipolar disorder (BD), but the findings of behavioral studies are often negative due to suboptimal sensitivity of the employed paradigms. This study aimed to investigate whether visual gaze patterns and facial displays of emotion during emotional film clips can reveal subtle behavioral abnormalities in remitted BD patients. METHODS.: Thirty-eight BD patients in full or partial remission and 40 healthy controls viewed 7 emotional film clips. These included happy, sad, and neutral scenarios and scenarios involving winning, risk-taking, and thrill-seeking behavior of relevance to the BD phenotype. Eye gaze and facial expressions were recorded during the film clips, and participants rated their emotional reactions after each clip. RESULTS.: BD patients showed a negative bias in both facial displays of emotion and self-rated emotional responses. Specifically, patients exhibited more fearful facial expressions during all film clips. This was accompanied by less positive self-rated emotions during the winning and happy film clips, and more negative emotions during the risk-taking/thrill-related film clips. CONCLUSIONS.: These findings suggest that BD is associated with trait-related abnormalities in subtle behavioral displays of emotion processing. Future studies comparing patients with BD and unipolar depression are warranted to clarify whether these differences are specific to BD. If so, assessments of visual gaze and facial displays of emotion during emotional film clips may have the potential to be implemented in clinical assessments to aid diagnostic accuracy.",
keywords = "Bipolar disorder, emotion reactivity, eye-tracking, facial expression, film clips, Bipolar Disorder/psychology, Humans, Middle Aged, Facial Expression, Male, Emotions/physiology, Fixation, Ocular, Case-Control Studies, Young Adult, Adult, Female, Photic Stimulation",
author = "Kj{\ae}rstad, {Hanne Lie} and J{\o}rgensen, {Caroline Kamp} and Ingrid Broch-Due and Kessing, {Lars Vedel} and Kamilla Miskowiak",
year = "2020",
month = feb,
day = "27",
doi = "10.1192/j.eurpsy.2020.26",
language = "English",
volume = "63",
pages = "e29",
journal = "European Psychiatry",
issn = "0924-9338",
publisher = "Elsevier France Editions Scientifiques et Medicales",
number = "1",

}

RIS

TY - JOUR

T1 - Eye gaze and facial displays of emotion during emotional film clips in remitted patients with bipolar disorder

AU - Kjærstad, Hanne Lie

AU - Jørgensen, Caroline Kamp

AU - Broch-Due, Ingrid

AU - Kessing, Lars Vedel

AU - Miskowiak, Kamilla

PY - 2020/2/27

Y1 - 2020/2/27

N2 - BACKGROUND.: Aberrant emotional reactivity is a putative endophenotype for bipolar disorder (BD), but the findings of behavioral studies are often negative due to suboptimal sensitivity of the employed paradigms. This study aimed to investigate whether visual gaze patterns and facial displays of emotion during emotional film clips can reveal subtle behavioral abnormalities in remitted BD patients. METHODS.: Thirty-eight BD patients in full or partial remission and 40 healthy controls viewed 7 emotional film clips. These included happy, sad, and neutral scenarios and scenarios involving winning, risk-taking, and thrill-seeking behavior of relevance to the BD phenotype. Eye gaze and facial expressions were recorded during the film clips, and participants rated their emotional reactions after each clip. RESULTS.: BD patients showed a negative bias in both facial displays of emotion and self-rated emotional responses. Specifically, patients exhibited more fearful facial expressions during all film clips. This was accompanied by less positive self-rated emotions during the winning and happy film clips, and more negative emotions during the risk-taking/thrill-related film clips. CONCLUSIONS.: These findings suggest that BD is associated with trait-related abnormalities in subtle behavioral displays of emotion processing. Future studies comparing patients with BD and unipolar depression are warranted to clarify whether these differences are specific to BD. If so, assessments of visual gaze and facial displays of emotion during emotional film clips may have the potential to be implemented in clinical assessments to aid diagnostic accuracy.

AB - BACKGROUND.: Aberrant emotional reactivity is a putative endophenotype for bipolar disorder (BD), but the findings of behavioral studies are often negative due to suboptimal sensitivity of the employed paradigms. This study aimed to investigate whether visual gaze patterns and facial displays of emotion during emotional film clips can reveal subtle behavioral abnormalities in remitted BD patients. METHODS.: Thirty-eight BD patients in full or partial remission and 40 healthy controls viewed 7 emotional film clips. These included happy, sad, and neutral scenarios and scenarios involving winning, risk-taking, and thrill-seeking behavior of relevance to the BD phenotype. Eye gaze and facial expressions were recorded during the film clips, and participants rated their emotional reactions after each clip. RESULTS.: BD patients showed a negative bias in both facial displays of emotion and self-rated emotional responses. Specifically, patients exhibited more fearful facial expressions during all film clips. This was accompanied by less positive self-rated emotions during the winning and happy film clips, and more negative emotions during the risk-taking/thrill-related film clips. CONCLUSIONS.: These findings suggest that BD is associated with trait-related abnormalities in subtle behavioral displays of emotion processing. Future studies comparing patients with BD and unipolar depression are warranted to clarify whether these differences are specific to BD. If so, assessments of visual gaze and facial displays of emotion during emotional film clips may have the potential to be implemented in clinical assessments to aid diagnostic accuracy.

KW - Bipolar disorder

KW - emotion reactivity

KW - eye-tracking

KW - facial expression

KW - film clips

KW - Bipolar Disorder/psychology

KW - Humans

KW - Middle Aged

KW - Facial Expression

KW - Male

KW - Emotions/physiology

KW - Fixation, Ocular

KW - Case-Control Studies

KW - Young Adult

KW - Adult

KW - Female

KW - Photic Stimulation

UR - http://www.scopus.com/inward/record.url?scp=85082144379&partnerID=8YFLogxK

U2 - 10.1192/j.eurpsy.2020.26

DO - 10.1192/j.eurpsy.2020.26

M3 - Journal article

C2 - 32102706

VL - 63

SP - e29

JO - European Psychiatry

JF - European Psychiatry

SN - 0924-9338

IS - 1

ER -

ID: 59449288