Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) by colorectal cancer cells and adjacent stroma cells--associations with histopathology and patients outcome

Søren Astrup Jensen, Ben Vainer, Annette Bartels, Nils Aage Brünner, Jens Benn Sørensen

40 Citationer (Scopus)

Abstract

To elucidate cellular features accountable for colorectal cancers' (CRC) capability to invade normal tissue and to metastasize, we investigated the level of the collagenase matrix metalloproteinase 9 (MMP-9) and its physiological inhibitor tissue inhibitor of metalloproteinases 1 (TIMP-1) in cancer cells and supporting stroma cells of CRC.
OriginalsprogEngelsk
TidsskriftEuropean journal of cancer (Oxford, England : 1990)
Vol/bind46
Udgave nummer18
Sider (fra-til)3233-42
Antal sider10
DOI
StatusUdgivet - 1 dec. 2010

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