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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Expression of fibroblast growth factor-21 in muscle is associated with lipodystrophy, insulin resistance and lipid disturbances in patients with HIV

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Vis graf over relationer
Fibroblast growth factor (FGF)-21 is a novel regulator of glucose and lipid metabolism. Recently, increased FGF-21 mRNA expression in muscle was found in patients with type 2 diabetes, but the role for FGF-21 in muscle is not well understood. Patients with HIV-infection and lipodystrophy are characterised by various degree of lipid-driven insulin resistance. We hypothesized that muscle FGF-21 mRNA would be altered in HIV patients with lipodystrophy.
OriginalsprogEngelsk
TidsskriftP L o S One
Vol/bind8
Udgave nummer3
Sider (fra-til)e55632
ISSN1932-6203
DOI
StatusUdgivet - 2013

ID: 40879085