Exercise training normalizes skeletal muscle vascular endothelial growth factor levels in patients with essential hypertension

Ane Håkansson Hansen, Jens Nielsen, Bengt Saltin, Ylva Hellsten

    47 Citationer (Scopus)

    Abstract

    Vascular endothelial growth factor (VEGF) protein and capillarization were determined in muscle vastus lateralis biopsy samples in individuals with essential hypertension (n = 10) and normotensive controls (n = 10). The hypertensive individuals performed exercise training for 16 weeks. Muscle samples as well as muscle microdialysis fluid samples were obtained at rest, during and after an acute exercise bout, performed prior to and after the training period, for the determination of muscle VEGF levels, VEGF release, endothelial cell proliferative effect and capillarization.
    OriginalsprogEngelsk
    TidsskriftJournal of Hypertension
    Vol/bind28
    Udgave nummer6
    Sider (fra-til)1176-85
    Antal sider10
    DOI
    StatusUdgivet - 1 jun. 2010

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