Evidence for formation of hydroxyl radicals during reperfusion after global cerebral ischaemia in rats using salicylate trapping and microdialysis

Keyphrases

• Microdialysis 100%
• Reperfusion 100%
• Hydroxyl Radical 100%
• Global Cerebral Ischemia 100%
• 2,5-Dihydroxybenzoic Acid 100%
• Salicylate 100%
• Striatum 80%
• Hippocampus 60%
• Fe2+ 60%
• Perfusion Fluid 40%
• 2,3-dihydroxybenzoic Acid 40%
• Ischemia 20%
• Fold Increase 20%
• Hypotension 20%
• Observation Period 20%
• Microdialysis Probe 20%
• Basal Level 20%
• Systemic Administration 20%
• One-group 20%
• Dialysate 20%
• Electrochemical Detection 20%
• Cerebral Microdialysis 20%
• Ultra-high Performance Liquid Chromatography (UHPLC) 20%
• OH Formation 20%
• Chromatogram 20%
• 3,5-dihydroxybenzoic Acid 20%
• Free Oxygen Radicals 20%
• Dihydroxybenzoic Acid 20%
• Four-vessel Occlusion 20%

Neuroscience

• Microdialysis 100%
• Brain Ischemia 100%
• Salicylate 100%
• Striatum 80%
• Hippocampus 60%
• Vitamin C 60%
• In Vivo 20%
• Ischemia 20%