Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Evaluation of immuview RSV antigen test (SSI siagnostica) and BinaxNOW RSV card (alere) for rapid detection of respiratory syncytial virus in retrospectively and prospectively collected respiratory samples

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Risk factors for genital human papillomavirus among men in Tanzania

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Detection of oncogenic genital human papillomavirus (HPV) among HPV negative older and younger women after 7 years of follow-up

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. SARS-CoV-2 detection using reverse transcription strand invasion based amplification and a portable compact size instrument

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Point of care testing for infectious disease: ownership and quality

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. A non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of SARS-CoV-2 RNA

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Human orthopneumovirus, formerly known as respiratory syncytial virus (RSV), is a frequent cause of hospitalization among infants due to respiratory tract infection. Fast, reliable, and easy to perform tests are needed to optimize treatment and to identify children that should be contact isolated to avoid nosocomial outbreaks. We prospectively tested 200 respiratory samples with a new assay (ImmuView RSV Antigen Test, SSI Diagnostica) and compared the results to the Alere BinaxNOW RSV Card by using our laboratory-developed real-time reverse transcription polymerase chain reaction (PCR) as reference. In addition, 300 retrospectively collected respiratory samples were included in the study. The sensitivities of both antigen kits were very low (<50%). Sensitivities were higher when samples came from children less than 6 years, when samples came from nasopharynx or lower respiratory airways, or when samples were positive for RSV serotype A compared to when samples came from adults, samples were throat swabs, or samples were positive for RSV serotype B. In conclusion, the ImmuView RSV antigen kit did not perform well and may at the most be used as a quick guidance for clinical decision. Thus, it cannot stand alone without reverse transcription PCR confirmation of negative results.

OriginalsprogEngelsk
TidsskriftJournal of Medical Virology
Vol/bind92
Udgave nummer12
Sider (fra-til)2992-2998
Antal sider7
ISSN0146-6615
DOI
StatusUdgivet - 1 dec. 2020

ID: 60545190