Evaluation of fusidic acid in therapy of experimental Staphylococcus aureus meningitis

Christian Østergaard; Runa Vavia Yieng-Kow; Jenny Dahl Knudsen; Niels Frimodt-Møller; Frank Espersen

doi:10.1093/jac/dkg231

Evaluation of fusidic acid in therapy of experimental Staphylococcus aureus meningitis

Christian Østergaard, Runa Vavia Yieng-Kow, Jenny Dahl Knudsen, Niels Frimodt-Møller, Frank Espersen

Klinisk Mikrobiologisk Afdeling

13 Citationer (Scopus)

Abstract

Udgivelsesdato: 2003-May

Originalsprog	Engelsk
Tidsskrift	Journal of Antimicrobial Chemotherapy
Vol/bind	51
Udgave nummer	5
Sider (fra-til)	1301-5
Antal sider	4
ISSN	0305-7453
DOI	https://doi.org/10.1093/jac/dkg231
Status	Udgivet - 2003

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10.1093/jac/dkg231

Citationsformater

@article{fdb2d8f649e44397b7adbbab57d79b54,

title = "Evaluation of fusidic acid in therapy of experimental Staphylococcus aureus meningitis",

abstract = "Combination therapy that includes fusidic acid, an antimicrobial agent highly active against staphylococci, has been recommended in the treatment of patients with Staphylococcus aureus meningitis. The aim of this study was to evaluate the pharmacokinetic, CSF bactericidal and anti-inflammatory properties of fusidic acid.",

keywords = "Animals, Anti-Bacterial Agents, Drug Therapy, Combination, Fusidic Acid, Glucose, Interleukin-8, Leukocyte Count, Meningitis, Bacterial, Methicillin, Microbial Sensitivity Tests, Penicillins, Rabbits, Staphylococcal Infections, Staphylococcus aureus",

author = "Christian {\O}stergaard and Yieng-Kow, {Runa Vavia} and Knudsen, {Jenny Dahl} and Niels Frimodt-M{\o}ller and Frank Espersen",

year = "2003",

doi = "10.1093/jac/dkg231",

language = "English",

volume = "51",

pages = "1301--5",

journal = "Journal of Antimicrobial Chemotherapy",

issn = "0305-7453",

publisher = "Oxford University Press",

number = "5",

}

TY - JOUR

T1 - Evaluation of fusidic acid in therapy of experimental Staphylococcus aureus meningitis

AU - Østergaard, Christian

AU - Yieng-Kow, Runa Vavia

AU - Knudsen, Jenny Dahl

AU - Frimodt-Møller, Niels

AU - Espersen, Frank

PY - 2003

Y1 - 2003

N2 - Combination therapy that includes fusidic acid, an antimicrobial agent highly active against staphylococci, has been recommended in the treatment of patients with Staphylococcus aureus meningitis. The aim of this study was to evaluate the pharmacokinetic, CSF bactericidal and anti-inflammatory properties of fusidic acid.

AB - Combination therapy that includes fusidic acid, an antimicrobial agent highly active against staphylococci, has been recommended in the treatment of patients with Staphylococcus aureus meningitis. The aim of this study was to evaluate the pharmacokinetic, CSF bactericidal and anti-inflammatory properties of fusidic acid.

KW - Animals

KW - Anti-Bacterial Agents

KW - Drug Therapy, Combination

KW - Fusidic Acid

KW - Glucose

KW - Interleukin-8

KW - Leukocyte Count

KW - Meningitis, Bacterial

KW - Methicillin

KW - Microbial Sensitivity Tests

KW - Penicillins

KW - Rabbits

KW - Staphylococcal Infections

KW - Staphylococcus aureus

U2 - 10.1093/jac/dkg231

DO - 10.1093/jac/dkg231

M3 - Journal article

C2 - 12697637

SN - 0305-7453

VL - 51

SP - 1301

EP - 1305

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

IS - 5

ER -

Evaluation of fusidic acid in therapy of experimental Staphylococcus aureus meningitis

Abstract

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