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Evaluation of different coatings of the tibial tray in uncemented total knee arthroplasty. A randomized controlled trial with 5 years follow-up with RSA and DEXA

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@article{f05a3ee76aa8489b85a0322e55aafd38,
title = "Evaluation of different coatings of the tibial tray in uncemented total knee arthroplasty. A randomized controlled trial with 5 years follow-up with RSA and DEXA",
abstract = "Background: Regenerex{\textregistered} is a porous titanium construct with a 3D interconnecting pore structure and biomechanical characteristics close to that of normal trabecular bone. This study aimed to compare the Regenerex (VR) to the non-interconnecting pore structure Porous Plasma Spray (VP) on tibial implants for total knee arthroplasty (TKA) at 5 years. Methods: We enrolled and randomized 61 patients (mean age = 63(49–71) years, Female/Male = 35/26) who were planned for an uncemented Vanguard TKA (Biomet, Warsaw, Indiana, USA) to receive either a VR or a VP coated tibial component (31/29). We performed radiostereometric analysis (RSA) and Dual Energy X-ray Absorptiometry (DEXA) postoperatively, and at three, six, 12, 24 and 60 months with measurements of migration. In total 55 patients attended the 5-year follow-up. Results: One patient died and four were reoperated during the 60-months period; none due to aseptic loosening. All reoperations were in the VR-group. The mean (range) 60-months MTPM was 1.4 mm (0.5–3.7) for the VP-group and 1.8 mm (0.4–4.9) for the VR-group (p = 0.8). The 24 to 60-months mean (range) MTPM was −0.3 mm (−5 to 1.24) in the VP-group and 0.2 mm (−0.4 to 3.5) in the VR-group (p = 0.8). Conclusion: We did not find any statistically significant differences between the VP- and VR-group and both groups show recognizable migration. We will continue to follow the groups for years to come.",
keywords = "Dual energy X-ray absorptiometry, Primary, Radiostereometric analysis, TKA, Total knee arthroplasty, Uncemented, Reoperation, Bone Density, Follow-Up Studies, Knee Prosthesis, Humans, Middle Aged, Male, Absorptiometry, Photon, Arthroplasty, Replacement, Knee/instrumentation, Biomechanical Phenomena, Radiostereometric Analysis, Titanium, Female, Aged, Porosity, Tibia/diagnostic imaging",
author = "Karen Dyreborg and Nikolaj Winther and Thomas Lind and Gunnar Flivik and {M{\o}rk Petersen}, Michael",
note = "Funding Information: Financial support for the 5-year follow-up that is presented in this article was received from Lima corporate S.p.A. (Udine, Italy) and the original 2-year follow-up was funded by a research grant from Biomet (Dordrecht, The Netherlands). The companies did not take part in the planning, data collection, analysis, interpretation of the results, or in writing the manuscript. Besides the above funding, the authors GF and MMP reports potential conflicts of interest with regards to research grants and representation outside this study (for details see the Declaration of Interest form). Publisher Copyright: {\textcopyright} 2021 The Authors Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = mar,
day = "1",
doi = "10.1016/j.knee.2021.02.002",
language = "English",
volume = "29",
pages = "208--215",
journal = "Knee",
issn = "0968-0160",
publisher = "Elsevier BV",

}

RIS

TY - JOUR

T1 - Evaluation of different coatings of the tibial tray in uncemented total knee arthroplasty. A randomized controlled trial with 5 years follow-up with RSA and DEXA

AU - Dyreborg, Karen

AU - Winther, Nikolaj

AU - Lind, Thomas

AU - Flivik, Gunnar

AU - Mørk Petersen, Michael

N1 - Funding Information: Financial support for the 5-year follow-up that is presented in this article was received from Lima corporate S.p.A. (Udine, Italy) and the original 2-year follow-up was funded by a research grant from Biomet (Dordrecht, The Netherlands). The companies did not take part in the planning, data collection, analysis, interpretation of the results, or in writing the manuscript. Besides the above funding, the authors GF and MMP reports potential conflicts of interest with regards to research grants and representation outside this study (for details see the Declaration of Interest form). Publisher Copyright: © 2021 The Authors Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/3/1

Y1 - 2021/3/1

N2 - Background: Regenerex® is a porous titanium construct with a 3D interconnecting pore structure and biomechanical characteristics close to that of normal trabecular bone. This study aimed to compare the Regenerex (VR) to the non-interconnecting pore structure Porous Plasma Spray (VP) on tibial implants for total knee arthroplasty (TKA) at 5 years. Methods: We enrolled and randomized 61 patients (mean age = 63(49–71) years, Female/Male = 35/26) who were planned for an uncemented Vanguard TKA (Biomet, Warsaw, Indiana, USA) to receive either a VR or a VP coated tibial component (31/29). We performed radiostereometric analysis (RSA) and Dual Energy X-ray Absorptiometry (DEXA) postoperatively, and at three, six, 12, 24 and 60 months with measurements of migration. In total 55 patients attended the 5-year follow-up. Results: One patient died and four were reoperated during the 60-months period; none due to aseptic loosening. All reoperations were in the VR-group. The mean (range) 60-months MTPM was 1.4 mm (0.5–3.7) for the VP-group and 1.8 mm (0.4–4.9) for the VR-group (p = 0.8). The 24 to 60-months mean (range) MTPM was −0.3 mm (−5 to 1.24) in the VP-group and 0.2 mm (−0.4 to 3.5) in the VR-group (p = 0.8). Conclusion: We did not find any statistically significant differences between the VP- and VR-group and both groups show recognizable migration. We will continue to follow the groups for years to come.

AB - Background: Regenerex® is a porous titanium construct with a 3D interconnecting pore structure and biomechanical characteristics close to that of normal trabecular bone. This study aimed to compare the Regenerex (VR) to the non-interconnecting pore structure Porous Plasma Spray (VP) on tibial implants for total knee arthroplasty (TKA) at 5 years. Methods: We enrolled and randomized 61 patients (mean age = 63(49–71) years, Female/Male = 35/26) who were planned for an uncemented Vanguard TKA (Biomet, Warsaw, Indiana, USA) to receive either a VR or a VP coated tibial component (31/29). We performed radiostereometric analysis (RSA) and Dual Energy X-ray Absorptiometry (DEXA) postoperatively, and at three, six, 12, 24 and 60 months with measurements of migration. In total 55 patients attended the 5-year follow-up. Results: One patient died and four were reoperated during the 60-months period; none due to aseptic loosening. All reoperations were in the VR-group. The mean (range) 60-months MTPM was 1.4 mm (0.5–3.7) for the VP-group and 1.8 mm (0.4–4.9) for the VR-group (p = 0.8). The 24 to 60-months mean (range) MTPM was −0.3 mm (−5 to 1.24) in the VP-group and 0.2 mm (−0.4 to 3.5) in the VR-group (p = 0.8). Conclusion: We did not find any statistically significant differences between the VP- and VR-group and both groups show recognizable migration. We will continue to follow the groups for years to come.

KW - Dual energy X-ray absorptiometry

KW - Primary

KW - Radiostereometric analysis

KW - TKA

KW - Total knee arthroplasty

KW - Uncemented

KW - Reoperation

KW - Bone Density

KW - Follow-Up Studies

KW - Knee Prosthesis

KW - Humans

KW - Middle Aged

KW - Male

KW - Absorptiometry, Photon

KW - Arthroplasty, Replacement, Knee/instrumentation

KW - Biomechanical Phenomena

KW - Radiostereometric Analysis

KW - Titanium

KW - Female

KW - Aged

KW - Porosity

KW - Tibia/diagnostic imaging

UR - http://www.scopus.com/inward/record.url?scp=85101585547&partnerID=8YFLogxK

U2 - 10.1016/j.knee.2021.02.002

DO - 10.1016/j.knee.2021.02.002

M3 - Journal article

C2 - 33647748

AN - SCOPUS:85101585547

VL - 29

SP - 208

EP - 215

JO - Knee

JF - Knee

SN - 0968-0160

ER -

ID: 66399389