Evaluation of 4-[(18)F]fluorobenzoyl-FALGEA-NH(2) as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer

Charlotte Lund Denholt; Tina Binderup; Marie-Thérése Stockhausen; Hans Skovgaard Poulsen; Mogens Spang-Thomsen; Paul Robert Hansen; Nic Gillings; Andreas Kjær

doi:10.1016/j.nucmedbio.2010.11.003

Evaluation of 4-[(18)F]fluorobenzoyl-FALGEA-NH(2) as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer

Charlotte Lund Denholt, Tina Binderup, Marie-Thérése Stockhausen, Hans Skovgaard Poulsen, Mogens Spang-Thomsen, Paul Robert Hansen, Nic Gillings, Andreas Kjær

Afdeling for Klinisk Fysiologi og Nuklearmedicin DIA

19 Citationer (Scopus)

Abstract

This study describes the radiosynthesis, in vitro and in vivo evaluation of the novel small peptide radioligand, 4-[(18)F]fluorobenzoyl-Phe-Ala-Leu-Gly-Glu-Ala-NH(2,) ([(18)F]FBA-FALGEA-NH(2)) as a positron emission tomography (PET) tracer for imaging of the cancer specific epidermal growth factor receptor (EGFR) variant III mutation, EGFRvIII.

Originalsprog	Engelsk
Tidsskrift	Nuclear Medicine and Biology
Vol/bind	38
Udgave nummer	4
Sider (fra-til)	509-15
Antal sider	7
ISSN	0969-8051
DOI	https://doi.org/10.1016/j.nucmedbio.2010.11.003
Status	Udgivet - maj 2011

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Denholt, C. L., Binderup, T., Stockhausen, M.-T., Poulsen, H. S., Spang-Thomsen, M., Hansen, P. R., Gillings, N., & Kjær, A. (2011). Evaluation of 4-[(18)F]fluorobenzoyl-FALGEA-NH(2) as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer. Nuclear Medicine and Biology, 38(4), 509-15. https://doi.org/10.1016/j.nucmedbio.2010.11.003

Evaluation of 4-[(18)F]fluorobenzoyl-FALGEA-NH(2) as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer. / Denholt, Charlotte Lund; Binderup, Tina; Stockhausen, Marie-Thérése et al.
I: Nuclear Medicine and Biology, Bind 38, Nr. 4, 05.2011, s. 509-15.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Denholt, CL, Binderup, T, Stockhausen, M-T, Poulsen, HS, Spang-Thomsen, M, Hansen, PR, Gillings, N & Kjær, A 2011, 'Evaluation of 4-[(18)F]fluorobenzoyl-FALGEA-NH(2) as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer', Nuclear Medicine and Biology, bind 38, nr. 4, s. 509-15. https://doi.org/10.1016/j.nucmedbio.2010.11.003

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abstract = "This study describes the radiosynthesis, in vitro and in vivo evaluation of the novel small peptide radioligand, 4-[(18)F]fluorobenzoyl-Phe-Ala-Leu-Gly-Glu-Ala-NH(2,) ([(18)F]FBA-FALGEA-NH(2)) as a positron emission tomography (PET) tracer for imaging of the cancer specific epidermal growth factor receptor (EGFR) variant III mutation, EGFRvIII.",

author = "Denholt, \{Charlotte Lund\} and Tina Binderup and Marie-Th{\'e}r{\'e}se Stockhausen and Poulsen, \{Hans Skovgaard\} and Mogens Spang-Thomsen and Hansen, \{Paul Robert\} and Nic Gillings and Andreas Kj{\ae}r",

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doi = "10.1016/j.nucmedbio.2010.11.003",

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AU - Denholt, Charlotte Lund

AU - Binderup, Tina

AU - Stockhausen, Marie-Thérése

AU - Poulsen, Hans Skovgaard

AU - Spang-Thomsen, Mogens

AU - Hansen, Paul Robert

AU - Gillings, Nic

AU - Kjær, Andreas

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AB - This study describes the radiosynthesis, in vitro and in vivo evaluation of the novel small peptide radioligand, 4-[(18)F]fluorobenzoyl-Phe-Ala-Leu-Gly-Glu-Ala-NH(2,) ([(18)F]FBA-FALGEA-NH(2)) as a positron emission tomography (PET) tracer for imaging of the cancer specific epidermal growth factor receptor (EGFR) variant III mutation, EGFRvIII.

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Evaluation of 4-[(18)F]fluorobenzoyl-FALGEA-NH(2) as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer

Abstract

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