Evaluation of 4-[(18)F]fluorobenzoyl-FALGEA-NH(2) as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer

Charlotte Lund Denholt, Tina Binderup, Marie-Thérése Stockhausen, Hans Skovgaard Poulsen, Mogens Spang-Thomsen, Paul Robert Hansen, Nic Gillings, Andreas Kjær

16 Citationer (Scopus)

Abstract

This study describes the radiosynthesis, in vitro and in vivo evaluation of the novel small peptide radioligand, 4-[(18)F]fluorobenzoyl-Phe-Ala-Leu-Gly-Glu-Ala-NH(2,) ([(18)F]FBA-FALGEA-NH(2)) as a positron emission tomography (PET) tracer for imaging of the cancer specific epidermal growth factor receptor (EGFR) variant III mutation, EGFRvIII.
OriginalsprogEngelsk
TidsskriftNuclear Medicine and Biology
Vol/bind38
Udgave nummer4
Sider (fra-til)509-15
Antal sider7
ISSN0969-8051
DOI
StatusUdgivet - maj 2011

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