TY - JOUR
T1 - Evaluation and proposal for optimization of neurophysiological tests in migraine
T2 - part 2--neuroimaging and the nitroglycerin test
AU - Magis, D
AU - Bendtsen, L
AU - Goadsby, P J
AU - May, A
AU - Sánchez del Rio, M
AU - Sandór, P S
AU - Kaube, H
AU - Sandrini, G
AU - Schoonman, G G
AU - Schoenen, J
AU - Afridi, S
AU - EUROHEAD Project
PY - 2007/12
Y1 - 2007/12
N2 - Neuroimaging methods have been widely used in headache and migraine research. They have provided invaluable information on brain perfusion, metabolism and structure during and outside of migraine attacks, contributing to an improved understanding of the pathophysiology of the disorder. Human models of migraine attacks are indispensable tools in pathophysiological and therapeutic research. This review of neuroimaging methods and the attack-provoking nitroglycerin test is part an initiative by a task force within the EUROHEAD project (EU Strep LSHM-CT-2004-5044837-Workpackage 9) with the objective of critically evaluating neurophysiological tests used in migraine. The first part, presented in a companion paper, is devoted to electrophysiological methods, this second part to neuroimaging methods such as functional magnetic resonance imaging, positron emission tomography and voxel-based morphometry, as well as the nitroglycerin test. For each of these methods, we summarize the results, analyse the methodological limitations and propose recommendations for improved methodology and standardization of research protocols.
AB - Neuroimaging methods have been widely used in headache and migraine research. They have provided invaluable information on brain perfusion, metabolism and structure during and outside of migraine attacks, contributing to an improved understanding of the pathophysiology of the disorder. Human models of migraine attacks are indispensable tools in pathophysiological and therapeutic research. This review of neuroimaging methods and the attack-provoking nitroglycerin test is part an initiative by a task force within the EUROHEAD project (EU Strep LSHM-CT-2004-5044837-Workpackage 9) with the objective of critically evaluating neurophysiological tests used in migraine. The first part, presented in a companion paper, is devoted to electrophysiological methods, this second part to neuroimaging methods such as functional magnetic resonance imaging, positron emission tomography and voxel-based morphometry, as well as the nitroglycerin test. For each of these methods, we summarize the results, analyse the methodological limitations and propose recommendations for improved methodology and standardization of research protocols.
KW - Diagnostic Imaging/methods
KW - Humans
KW - Italy
KW - Migraine Disorders/diagnosis
KW - Neurophysiology/methods
KW - Nitroglycerin
KW - Practice Guidelines as Topic
KW - Quality Assurance, Health Care/methods
KW - Reproducibility of Results
KW - Sensitivity and Specificity
KW - Vasodilator Agents
U2 - 10.1111/j.1468-2982.2007.01435.x
DO - 10.1111/j.1468-2982.2007.01435.x
M3 - Review
C2 - 17970767
SN - 0333-1024
VL - 27
SP - 1339
EP - 1359
JO - Cephalalgia : an international journal of headache
JF - Cephalalgia : an international journal of headache
IS - 12
ER -