Evaluating Tumor Quantification in Place of Proportions in Prostate Cancer: Principles of the ProQuant Group

Andrew J Vickers; Samson Fine; ProQuant Group

doi:10.1016/j.eururo.2025.11.013

Evaluating Tumor Quantification in Place of Proportions in Prostate Cancer: Principles of the ProQuant Group

Andrew J Vickers^*
, Samson Fine
, ProQuant Group

^*Corresponding author af dette arbejde

Afdeling for Urinvejskirurgi

Abstract

We describe the rationale for using quantification of Gleason pattern 4 rather than the proportion of Gleason patterns for risk stratification in prostate cancer, as proposed by the ProQuant Group. We outline research that will be conducted to assess this strategy, and invite individuals interested in collaboration to join the group.

Originalsprog	Engelsk
Tidsskrift	European Urology
Vol/bind	89
Udgave nummer	4
Sider (fra-til)	298-301
Antal sider	4
ISSN	0302-2838
DOI	https://doi.org/10.1016/j.eururo.2025.11.013
Status	Udgivet - apr. 2026

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10.1016/j.eururo.2025.11.013

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title = "Evaluating Tumor Quantification in Place of Proportions in Prostate Cancer: Principles of the ProQuant Group",

abstract = "We describe the rationale for using quantification of Gleason pattern 4 rather than the proportion of Gleason patterns for risk stratification in prostate cancer, as proposed by the ProQuant Group. We outline research that will be conducted to assess this strategy, and invite individuals interested in collaboration to join the group.",

keywords = "Humans, Male, Prostatic Neoplasms/pathology, Neoplasm Grading, Risk Assessment",

author = "Vickers, \{Andrew J\} and Samson Fine and Andreas R{\o}der and Stroomberg, \{Hein Vincent\} and \{ProQuant Group\}",

year = "2026",

month = apr,

doi = "10.1016/j.eururo.2025.11.013",

language = "English",

volume = "89",

pages = "298--301",

journal = "European Urology",

issn = "0302-2838",

publisher = "Elsevier BV",

number = "4",

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T1 - Evaluating Tumor Quantification in Place of Proportions in Prostate Cancer

T2 - Principles of the ProQuant Group

AU - Vickers, Andrew J

AU - Fine, Samson

AU - ProQuant Group

A2 - Røder, Andreas

A2 - Stroomberg, Hein Vincent

PY - 2026/4

Y1 - 2026/4

N2 - We describe the rationale for using quantification of Gleason pattern 4 rather than the proportion of Gleason patterns for risk stratification in prostate cancer, as proposed by the ProQuant Group. We outline research that will be conducted to assess this strategy, and invite individuals interested in collaboration to join the group.

AB - We describe the rationale for using quantification of Gleason pattern 4 rather than the proportion of Gleason patterns for risk stratification in prostate cancer, as proposed by the ProQuant Group. We outline research that will be conducted to assess this strategy, and invite individuals interested in collaboration to join the group.

KW - Humans

KW - Male

KW - Prostatic Neoplasms/pathology

KW - Neoplasm Grading

KW - Risk Assessment

UR - https://www.scopus.com/pages/publications/105033960338

U2 - 10.1016/j.eururo.2025.11.013

DO - 10.1016/j.eururo.2025.11.013

M3 - Editorial

C2 - 41419390

SN - 0302-2838

VL - 89

SP - 298

EP - 301

JO - European Urology

JF - European Urology

IS - 4

ER -

Evaluating Tumor Quantification in Place of Proportions in Prostate Cancer: Principles of the ProQuant Group

Abstract

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