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EUS tissue acquisition: From A to B

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. An international, multi-institution survey on performing EUS-FNA and fine needle biopsy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. What should be known prior to performing EUS exams? (Part II)

    Publikation: Bidrag til tidsskriftReviewpeer review

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EUS-guided tissue acquisition (EUS-TA) has made rapid development since its introduction in the early 1990s. The technique is widely accepted and invaluable for staging and diagnosis of a variety of upper gastrointestinal and mediastinal lesions. Fine-needle aspiration (FNA) has long been the gold standard, but due to its limitations such as the inability to retain stroma and associated cellular architecture, novel biopsy needles (FNB) were designed. Overall, FNA and FNB needles perform seemingly equally in terms of diagnostic accuracy, however, the second-generation FNB needles require less passes. The third-generation FNB needles (crown-cut needle types) seem to be preferable to FNA needles as well as to the second-generation FNB needles, when larger histological specimens and preserved tissue architecture are required. EUS-TA is constantly under development, and new applications of this technique include tumor risk stratification according to its genetic profile as well as minimally invasive creation of patient-derived organoids, hallmarks of personized medicine. It remains yet to be shown, whether these applications will lead to a decisive shift from aspiration to biopsy, i.e., from A to B.
OriginalsprogEngelsk
TidsskriftEndoscopic Ultrasound
Vol/bind9
Udgave nummer4
Sider (fra-til)225-231
ISSN2303-9027
StatusUdgivet - 2020

ID: 61414076