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European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager: Mohamed R. Daha

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. The ficolin response to LPS challenge in mice

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Amyotrophic lateral sclerosis: The complement and inflammatory hypothesis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Common and rare genetic variants of complement components in human disease

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Complement activation by cholesterol crystals triggers a subsequent cytokine response

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Ficolins and the lectin pathway of complement in patients with systemic lupus erythematosus

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Prediction of survival in amyotrophic lateral sclerosis: a nationwide, Danish cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Reply to Lassaunière: On the functional characterization of the Y453F RBD variant found in cluster 5 SARS-CoV-2

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Functional Effects of Receptor-Binding Domain Mutations of SARS-CoV-2 B.1.351 and P.1 Variants

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Reinhard Würzner
  • Francesco Tedesco
  • Peter Garred
  • Tom Eirik Mollnes
  • Lennart Truedsson
  • Malcolm W Turner
  • Yngve Sommarin
  • Jörgen Wieslander
  • Robert B Sim
Vis graf over relationer

A whole complement ELISA-based assay kit, primarily designed to screen for deficiencies in components of the complement system was developed during a European Union grant involving more than a dozen European scientists and a small-medium enterprise company (Wieslab, which later merged into Eurodiagnostica). The consortium was led by Prof. Mohamed R. Daha who had already guided a preceding European grant which prepared the ground for this endeavor to create a novel and sophisticated complement measurement tool. The final result of the grant was a scientific publication (Seelen et al., 2005, J. Immunol. Methods 296, 187-198) and a commercially available complement deficiency screening kit, WIESLAB(®) Complement system Screen. Thereafter, the group decided to carry on with a grant, located at Innsbruck Medical University, and supported by royalties and unrestricted educational grants from Eurodiagnostica, Malmö, entitled "Search for Applications for WIESLAB(®) Complement system Screen (SAW)" with the aim to look for further applications of this assay. During the latter project the group organized several scientific meetings aimed at evaluating the use of the assay as well as developing further branches of its platform. A look back over almost two decades reveals a great story of excellent research which was also commercially successful, fulfilling the aims of European Union grants. It is also a story of ageless friendship, only possible due to the vision and guidance of an exceptional manager: Moh Daha.

OriginalsprogEngelsk
TidsskriftMolecular Immunology
Vol/bind68
Udgave nummer1
Sider (fra-til)63-6
Antal sider4
ISSN0161-5890
DOI
StatusUdgivet - nov. 2015

ID: 45855065