TY - JOUR
T1 - Etiology and epidemiology of catheter related bloodstream infections in patients receiving home parenteral nutrition in a gastromedical center at a tertiary hospital in denmark
AU - Nielsen, Xiaohui Chen
AU - Chen, Ming
AU - Hellesøe, Anne-Marie Blok
AU - Jeppesen, Palle Bekker
AU - Gyldenlykke, Jonna
AU - Tvede, Michael
AU - Andersen, Leif Percival
PY - 2012
Y1 - 2012
N2 - We conducted a retrospective epidemiologic study of catheter related bloodstream infections (CRBSI) in patients receiving long-term home parenteral nutrition (HPN) from January 2002 to December 2005. Our results showed that coagulase negative staphylococci (CoNS) were the most prevalent pathogens (44.7% of all CRBSI episodes), followed by Enterobacteriaceae (33.2%). Prevalence for candidemia and Enterococcus bacteremia was relatively high (14.4% and 10.8%, respectively). Cefuroxime resistance was observed in 65.4% CoNS and 31.5% Enterobacteriaceae. Based on the results from the study, a new empiric antimicrobial treatment regiment was suggested.
AB - We conducted a retrospective epidemiologic study of catheter related bloodstream infections (CRBSI) in patients receiving long-term home parenteral nutrition (HPN) from January 2002 to December 2005. Our results showed that coagulase negative staphylococci (CoNS) were the most prevalent pathogens (44.7% of all CRBSI episodes), followed by Enterobacteriaceae (33.2%). Prevalence for candidemia and Enterococcus bacteremia was relatively high (14.4% and 10.8%, respectively). Cefuroxime resistance was observed in 65.4% CoNS and 31.5% Enterobacteriaceae. Based on the results from the study, a new empiric antimicrobial treatment regiment was suggested.
U2 - 10.2174/1874285801206010098
DO - 10.2174/1874285801206010098
M3 - Journal article
C2 - 23248717
SN - 1874-2858
VL - 6
SP - 98
EP - 101
JO - The Open Microbiology Journal
JF - The Open Microbiology Journal
ER -