TY - JOUR
T1 - ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma
AU - Concin, Nicole
AU - Matias-Guiu, Xavier
AU - Vergote, Ignace
AU - Cibula, David
AU - Mirza, Mansoor Raza
AU - Marnitz, Simone
AU - Ledermann, Jonathan
AU - Bosse, Tjalling
AU - Chargari, Cyrus
AU - Fagotti, Anna
AU - Fotopoulou, Christina
AU - Martin, Antonio Gonzalez
AU - Lax, Sigurd
AU - Lorusso, Domenica
AU - Marth, Christian
AU - Morice, Philippe
AU - Nout, Remi A
AU - O'Donnell, Dearbhaile
AU - Querleu, Denis
AU - Raspollini, Maria Rosaria
AU - Sehouli, Jalid
AU - Sturdza, Alina
AU - Taylor, Alexandra
AU - Westermann, Anneke
AU - Wimberger, Pauline
AU - Colombo, Nicoletta
AU - Planchamp, François
AU - Creutzberg, Carien L
N1 - Copyright © 2021 International Gynecologic Cancer Society and European Society of Gynecological Oncology [Published by BMJ]; Springer Verlag GmbH Berlin Heidelberg, part of Springer Nature. Published by Elsevier B.V. All rights reserved.
PY - 2021/1
Y1 - 2021/1
N2 - A European consensus conference on endometrial carcinoma was held in 2014 to produce multidisciplinary evidence-based guidelines on selected questions. Given the large body of literature on the management of endometrial carcinoma published since 2014, the European Society of Gynaecological Oncology (ESGO), the European SocieTy for Radiotherapy & Oncology (ESTRO) and the European Society of Pathology (ESP) jointly decided to update these evidence-based guidelines and to cover new topics in order to improve the quality of care for women with endometrial carcinoma across Europe and worldwide. ESGO/ESTRO/ESP nominated an international multidisciplinary development group consisting of practicing clinicians and researchers who have demonstrated leadership and expertise in the care and research of endometrial carcinoma (27 experts across Europe). To ensure that the guidelines are evidence-based, the literature published since 2014, identified from a systematic search was reviewed and critically appraised. In the absence of any clear scientific evidence, judgment was based on the professional experience and consensus of the development group. The guidelines are thus based on the best available evidence and expert agreement. Prior to publication, the guidelines were reviewed by 191 independent international practitioners in cancer care delivery and patient representatives. The guidelines comprehensively cover endometrial carcinoma staging, definition of prognostic risk groups integrating molecular markers, pre- and intra-operative work-up, fertility preservation, management for early, advanced, metastatic, and recurrent disease and palliative treatment. Principles of radiotherapy and pathological evaluation are also defined.
AB - A European consensus conference on endometrial carcinoma was held in 2014 to produce multidisciplinary evidence-based guidelines on selected questions. Given the large body of literature on the management of endometrial carcinoma published since 2014, the European Society of Gynaecological Oncology (ESGO), the European SocieTy for Radiotherapy & Oncology (ESTRO) and the European Society of Pathology (ESP) jointly decided to update these evidence-based guidelines and to cover new topics in order to improve the quality of care for women with endometrial carcinoma across Europe and worldwide. ESGO/ESTRO/ESP nominated an international multidisciplinary development group consisting of practicing clinicians and researchers who have demonstrated leadership and expertise in the care and research of endometrial carcinoma (27 experts across Europe). To ensure that the guidelines are evidence-based, the literature published since 2014, identified from a systematic search was reviewed and critically appraised. In the absence of any clear scientific evidence, judgment was based on the professional experience and consensus of the development group. The guidelines are thus based on the best available evidence and expert agreement. Prior to publication, the guidelines were reviewed by 191 independent international practitioners in cancer care delivery and patient representatives. The guidelines comprehensively cover endometrial carcinoma staging, definition of prognostic risk groups integrating molecular markers, pre- and intra-operative work-up, fertility preservation, management for early, advanced, metastatic, and recurrent disease and palliative treatment. Principles of radiotherapy and pathological evaluation are also defined.
KW - Consensus
KW - Endometrial Neoplasms/radiotherapy
KW - Europe
KW - Female
KW - Guidelines as Topic
KW - Humans
KW - Radiation Oncology
KW - Risk Factors
UR - http://www.scopus.com/inward/record.url?scp=85102916477&partnerID=8YFLogxK
U2 - 10.1016/j.radonc.2020.11.018
DO - 10.1016/j.radonc.2020.11.018
M3 - Journal article
C2 - 33712263
SN - 0167-8140
VL - 154
SP - 327
EP - 353
JO - Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
JF - Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
ER -