Epstein-Barr-virus-associeret lymfom hos en patient med colitis ulcerosa i behandling med azathioprin

Kristian Kofoed, Marianne Kiszka-Kanowitz, Jens Mørch Albrectsen, Ove Andersen

2 Citationer (Scopus)

Abstract

A 28 year-old man with ulcerative colitis treated for 10 years with azathioprine (AZA) returned from Central Asia with fever, swollen lymph glands, hepatosplenomegaly, and pancytopenia. He was tested positive for acute Epstein-Barr virus (EBV) infection. Before the final diagnosis of EBV-associated large B-cell lymphoma was confirmed, he died from multiple organ failure. AZA and 6-mercaptopurine are associated with the development of EBV-positive lymphomas in organ-transplanted patients. This type of lymphoma is a rare complication in inflammatory bowel disease.
Bidragets oversatte titelEpstein-Barr virus-associated large B-cell lymphoma in a patient with colitis ulcerosa treated with azathioprine
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind170
Udgave nummer15
Sider (fra-til)1255
ISSN0041-5782
StatusUdgivet - 2008

Emneord

  • Adult
  • Azathioprine
  • Colitis, Ulcerative
  • Epstein-Barr Virus Infections
  • Fatal Outcome
  • Herpesvirus 4, Human
  • Humans
  • Immunosuppressive Agents
  • Lymphoma, B-Cell
  • Male
  • Multiple Organ Failure

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