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Epigenetic therapy in hematological cancers

Publikation: Bidrag til tidsskriftReviewForskningpeer review

DOI

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Vis graf over relationer

The increasing depth of knowledge about cancer biology throughout the last decades, has underlined the importance of not only genetic aberrations, but also epigenetic abnormalities in cancer cells. The extensive exploration of the cancer epigenome has provided insights into key pathways involved in tumorigenesis, as well as has allowed the development of novel epigenetic therapies. In this review, we will present the important role of epigenetic alterations in hematological diseases, with special focus on epigenetically-based targeting of hematological malignancies.

OriginalsprogEngelsk
TidsskriftAPMIS - Journal of Pathology, Microbiology and Immunology
Vol/bind127
Udgave nummer5
Sider (fra-til)316-328
Antal sider13
ISSN0903-4641
DOI
StatusUdgivet - 1 maj 2019

Bibliografisk note

© 2019 APMIS. Published by John Wiley & Sons Ltd.

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