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Epidemiology of Venous Thromboembolism After Second Cancer

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Harvard

Gade, IL, Severinsen, MT, Kragholm, KH, Kristensen, SR, Torp-Pedersen, C & Riddersholm, SJ 2020, 'Epidemiology of Venous Thromboembolism After Second Cancer' Clinical Epidemiology, bind 12, s. 377-386. https://doi.org/10.2147/CLEP.S247823

APA

Gade, I. L., Severinsen, M. T., Kragholm, K. H., Kristensen, S. R., Torp-Pedersen, C., & Riddersholm, S. J. (2020). Epidemiology of Venous Thromboembolism After Second Cancer. Clinical Epidemiology, 12, 377-386. https://doi.org/10.2147/CLEP.S247823

CBE

Gade IL, Severinsen MT, Kragholm KH, Kristensen SR, Torp-Pedersen C, Riddersholm SJ. 2020. Epidemiology of Venous Thromboembolism After Second Cancer. Clinical Epidemiology. 12:377-386. https://doi.org/10.2147/CLEP.S247823

MLA

Vancouver

Gade IL, Severinsen MT, Kragholm KH, Kristensen SR, Torp-Pedersen C, Riddersholm SJ. Epidemiology of Venous Thromboembolism After Second Cancer. Clinical Epidemiology. 2020;12:377-386. https://doi.org/10.2147/CLEP.S247823

Author

Gade, Inger Lise ; Severinsen, Marianne Tang ; Kragholm, Kristian Hay ; Kristensen, Søren Risom ; Torp-Pedersen, Christian ; Riddersholm, Signe Juul. / Epidemiology of Venous Thromboembolism After Second Cancer. I: Clinical Epidemiology. 2020 ; Bind 12. s. 377-386.

Bibtex

@article{e834d5c472404e04b789d8ddef34c5f2,
title = "Epidemiology of Venous Thromboembolism After Second Cancer",
abstract = "Background: Venous thromboembolism (VTE) is a serious, yet preventable, complication in cancer. Some patients are diagnosed with a second cancer; however, little is known about the epidemiology of VTE in this population.Methods: From Danish national healthcare registries, we studied all patients diagnosed with a first breast, prostate, lung, or colorectal cancer from 1995 to 2015. We estimated incidence rates (IRs) of VTE according to the timing of the diagnosis of a second cancer. We controlled for confounder variables in Poisson regression models.Results: In total, 309,077 patients with a first breast, prostate, lung, or colorectal cancer were included in the study. A second cancer was diagnosed in 20,090 (6.5{\%}) of these patients. In total, 11,908 VTEs were observed in the study period, 786 of these occurred after a diagnosis of second cancer. Second cancer types such as pancreas and stomach cancer were associated with fivefold higher IRs of VTE compared with second cancer types such as breast and prostate cancer. The IR of VTE was highest within the first 6 months after the second cancer was diagnosed (IR 40.5 per 1000 person-years, 95{\%} CI 36.3-42.2) with no differences based on how long since the first cancer it was diagnosed.Conclusion: The epidemiology of VTE after a second cancer is similar to the epidemiology of VTE after a first cancer with higher rates within the first months after aggressive second cancer types.",
author = "Gade, {Inger Lise} and Severinsen, {Marianne Tang} and Kragholm, {Kristian Hay} and Kristensen, {S{\o}ren Risom} and Christian Torp-Pedersen and Riddersholm, {Signe Juul}",
note = "{\circledC} 2020 Gade et al.",
year = "2020",
doi = "10.2147/CLEP.S247823",
language = "English",
volume = "12",
pages = "377--386",
journal = "Clinical Epidemiology",
issn = "1179-1349",
publisher = "Dove Medical Press Ltd",

}

RIS

TY - JOUR

T1 - Epidemiology of Venous Thromboembolism After Second Cancer

AU - Gade, Inger Lise

AU - Severinsen, Marianne Tang

AU - Kragholm, Kristian Hay

AU - Kristensen, Søren Risom

AU - Torp-Pedersen, Christian

AU - Riddersholm, Signe Juul

N1 - © 2020 Gade et al.

PY - 2020

Y1 - 2020

N2 - Background: Venous thromboembolism (VTE) is a serious, yet preventable, complication in cancer. Some patients are diagnosed with a second cancer; however, little is known about the epidemiology of VTE in this population.Methods: From Danish national healthcare registries, we studied all patients diagnosed with a first breast, prostate, lung, or colorectal cancer from 1995 to 2015. We estimated incidence rates (IRs) of VTE according to the timing of the diagnosis of a second cancer. We controlled for confounder variables in Poisson regression models.Results: In total, 309,077 patients with a first breast, prostate, lung, or colorectal cancer were included in the study. A second cancer was diagnosed in 20,090 (6.5%) of these patients. In total, 11,908 VTEs were observed in the study period, 786 of these occurred after a diagnosis of second cancer. Second cancer types such as pancreas and stomach cancer were associated with fivefold higher IRs of VTE compared with second cancer types such as breast and prostate cancer. The IR of VTE was highest within the first 6 months after the second cancer was diagnosed (IR 40.5 per 1000 person-years, 95% CI 36.3-42.2) with no differences based on how long since the first cancer it was diagnosed.Conclusion: The epidemiology of VTE after a second cancer is similar to the epidemiology of VTE after a first cancer with higher rates within the first months after aggressive second cancer types.

AB - Background: Venous thromboembolism (VTE) is a serious, yet preventable, complication in cancer. Some patients are diagnosed with a second cancer; however, little is known about the epidemiology of VTE in this population.Methods: From Danish national healthcare registries, we studied all patients diagnosed with a first breast, prostate, lung, or colorectal cancer from 1995 to 2015. We estimated incidence rates (IRs) of VTE according to the timing of the diagnosis of a second cancer. We controlled for confounder variables in Poisson regression models.Results: In total, 309,077 patients with a first breast, prostate, lung, or colorectal cancer were included in the study. A second cancer was diagnosed in 20,090 (6.5%) of these patients. In total, 11,908 VTEs were observed in the study period, 786 of these occurred after a diagnosis of second cancer. Second cancer types such as pancreas and stomach cancer were associated with fivefold higher IRs of VTE compared with second cancer types such as breast and prostate cancer. The IR of VTE was highest within the first 6 months after the second cancer was diagnosed (IR 40.5 per 1000 person-years, 95% CI 36.3-42.2) with no differences based on how long since the first cancer it was diagnosed.Conclusion: The epidemiology of VTE after a second cancer is similar to the epidemiology of VTE after a first cancer with higher rates within the first months after aggressive second cancer types.

U2 - 10.2147/CLEP.S247823

DO - 10.2147/CLEP.S247823

M3 - Journal article

VL - 12

SP - 377

EP - 386

JO - Clinical Epidemiology

JF - Clinical Epidemiology

SN - 1179-1349

ER -

ID: 59733664