Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial

Stig-Frederik Trojahn Kølle; Anne Fischer-Nielsen; Anders Bruun Mathiasen; Jens Jørgen Elberg; Roberto S Oliveri; Peter V Glovinski; Jens Kastrup; Eva Maria Kirchhoff; Bo Sonnich Rasmussen; Maj-Lis Talman; Carsten Thomsen; Ebbe Dickmeiss; Krzysztof Tadeusz Drzewiecki

doi:10.1016/S0140-6736(13)61410-5

Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial

Stig-Frederik Trojahn Kølle, Anne Fischer-Nielsen, Anders Bruun Mathiasen, Jens Jørgen Elberg, Roberto S Oliveri, Peter V Glovinski, Jens Kastrup, Eva Maria Kirchhoff, Bo Sonnich Rasmussen, Maj-Lis Talman, Carsten Thomsen, Ebbe Dickmeiss, Krzysztof Tadeusz Drzewiecki

430 Citationer (Scopus)

Abstract

Autologous fat grafting is increasingly used in reconstructive surgery. However, resorption rates ranging from 25% to 80% have been reported. Therefore, methods to increase graft viability are needed. Here, we report the results of a triple-blind, placebo-controlled trial to compare the survival of fat grafts enriched with autologous adipose-derived stem cells (ASCs) versus non-enriched fat grafts.

Originalsprog	Engelsk
Tidsskrift	Lancet
Vol/bind	382
Udgave nummer	9898
Sider (fra-til)	1113-20
Antal sider	8
ISSN	0140-6736
DOI	https://doi.org/10.1016/S0140-6736(13)61410-5
Status	Udgivet - 28 sep. 2013

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10.1016/S0140-6736(13)61410-5

Citationsformater

Kølle, S-F. T., Fischer-Nielsen, A., Mathiasen, A. B., Elberg, J. J., Oliveri, R. S., Glovinski, P. V., Kastrup, J., Kirchhoff, E. M., Rasmussen, B. S., Talman, M-L., Thomsen, C., Dickmeiss, E., & Drzewiecki, K. T. (2013). Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial. Lancet, 382(9898), 1113-20. https://doi.org/10.1016/S0140-6736(13)61410-5

Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival : a randomised placebo-controlled trial. / Kølle, Stig-Frederik Trojahn; Fischer-Nielsen, Anne; Mathiasen, Anders Bruun et al.

I: Lancet, Bind 382, Nr. 9898, 28.09.2013, s. 1113-20.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Kølle, S-FT, Fischer-Nielsen, A, Mathiasen, AB, Elberg, JJ, Oliveri, RS, Glovinski, PV , Kastrup, J , Kirchhoff, EM , Rasmussen, BS , Talman, M-L, Thomsen, C, Dickmeiss, E & Drzewiecki, KT 2013, 'Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial', Lancet, bind 382, nr. 9898, s. 1113-20. https://doi.org/10.1016/S0140-6736(13)61410-5

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title = "Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial",

abstract = "Autologous fat grafting is increasingly used in reconstructive surgery. However, resorption rates ranging from 25% to 80% have been reported. Therefore, methods to increase graft viability are needed. Here, we report the results of a triple-blind, placebo-controlled trial to compare the survival of fat grafts enriched with autologous adipose-derived stem cells (ASCs) versus non-enriched fat grafts.",

author = "K{\o}lle, {Stig-Frederik Trojahn} and Anne Fischer-Nielsen and Mathiasen, {Anders Bruun} and Elberg, {Jens J{\o}rgen} and Oliveri, {Roberto S} and Glovinski, {Peter V} and Jens Kastrup and Kirchhoff, {Eva Maria} and Rasmussen, {Bo Sonnich} and Maj-Lis Talman and Carsten Thomsen and Ebbe Dickmeiss and Drzewiecki, {Krzysztof Tadeusz}",

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doi = "10.1016/S0140-6736(13)61410-5",

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T2 - a randomised placebo-controlled trial

AU - Kølle, Stig-Frederik Trojahn

AU - Fischer-Nielsen, Anne

AU - Mathiasen, Anders Bruun

AU - Elberg, Jens Jørgen

AU - Oliveri, Roberto S

AU - Glovinski, Peter V

AU - Kastrup, Jens

AU - Kirchhoff, Eva Maria

AU - Rasmussen, Bo Sonnich

AU - Talman, Maj-Lis

AU - Thomsen, Carsten

AU - Dickmeiss, Ebbe

AU - Drzewiecki, Krzysztof Tadeusz

PY - 2013/9/28

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N2 - Autologous fat grafting is increasingly used in reconstructive surgery. However, resorption rates ranging from 25% to 80% have been reported. Therefore, methods to increase graft viability are needed. Here, we report the results of a triple-blind, placebo-controlled trial to compare the survival of fat grafts enriched with autologous adipose-derived stem cells (ASCs) versus non-enriched fat grafts.

AB - Autologous fat grafting is increasingly used in reconstructive surgery. However, resorption rates ranging from 25% to 80% have been reported. Therefore, methods to increase graft viability are needed. Here, we report the results of a triple-blind, placebo-controlled trial to compare the survival of fat grafts enriched with autologous adipose-derived stem cells (ASCs) versus non-enriched fat grafts.

U2 - 10.1016/S0140-6736(13)61410-5

DO - 10.1016/S0140-6736(13)61410-5

M3 - Journal article

C2 - 24075051

VL - 382

SP - 1113

EP - 1120

JO - Lancet

JF - Lancet

SN - 0140-6736

IS - 9898

ER -

Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial

Abstract

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