Abstract
INTRODUCTION: The number of kidney-transplanted patients is growing. This report describes the age, sex distribution, kidney function, graft age, and immunosuppressive drugs of kidney-transplanted patients followed at the outpatient clinic of the nephrology department at Copenhagen University Hospital, Herlev, Denmark.
MATERIALS AND METHODS: Cross-sectional study of all living kidney-transplanted patients with a functioning graft followed at Copenhagen University Hospital, Herlev (n=241). Data were extracted from patient records during November 2005-March 2006.
RESULTS: The sex distribution (131 males, 110 females) was equal. The average patient age was 52 years (SD 12), the average glomerular filtration rate 43 ml/min/1.73 m2 (range 6-114 ml/min/1.73 m2), and the average graft age was 8.3 years (range 0-28 years). Hyperparathyroidism was highly prevalent (64%). The majority of patients (74%) were treated with triple-drug immunosuppression, in most cases (46%) with the combination prednisolone-ciclosporine-azathioprine. During recent years, azathioprine has been increasingly replaced by mycophenolate mofetil.
CONCLUSIONS: The majority of kidney-transplanted patients with a functioning graft have sufficient kidney function to keep the patients free of uremic symptoms. Hyperparathyroidism is frequent. The immunosuppressive regimens used for kidney-transplanted patients are currently changing.
Bidragets oversatte titel | Kidney function and immunosuppression of kidney-transplanted patients |
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Originalsprog | Dansk |
Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 170 |
Udgave nummer | 19 |
Sider (fra-til) | 1658-62 |
Antal sider | 5 |
ISSN | 0041-5782 |
Status | Udgivet - 5 maj 2008 |
Emneord
- Adult
- Azathioprine
- Cross-Sectional Studies
- Cyclosporine
- Drug Therapy, Combination
- Female
- Follow-Up Studies
- Glomerular Filtration Rate
- Humans
- Hyperparathyroidism, Secondary
- Immunosuppressive Agents
- Kidney Transplantation
- Male
- Middle Aged
- Prednisolone
- Treatment Outcome