Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat

Keyphrases

• Tissue Inhibitor of metalloproteinase-1 (TIMP-1) 100%
• Matrix metalloproteinase-9 (MMP-9) 100%
• Cerebral Ischemia 100%
• MEK-ERK Pathway 100%
• Blood-brain Barrier 50%
• MMP-9 Inhibitor 50%
• U0126 33%
• Enhanced Expression 33%
• Infarct Volume 33%
• ERK2 33%
• Neurological Function 33%
• Vessel Wall 33%
• Transient Middle Cerebral Artery Occlusion (tMCAO) 33%
• Immunocytochemistry 33%
• Blood Flow 16%
• Smooth muscle Cells 16%
• MEK1 16%
• Confocal Microscopy 16%
• Infarct 16%
• Vascular Expression 16%
• Recirculation 16%
• Microvessels 16%
• Edema 16%
• Ischemic Events 16%
• Glial Markers 16%
• Blood Metabolism 16%
• Focal Ischemia 16%
• Astrocytes 16%
• Reduced Expression 16%

Neuroscience

• MMP9 100%
• Brain Ischemia 100%
• Metalloprotease Inhibitor 100%
• Blood Brain Barrier 42%
• Middle Cerebral Artery 28%
• Mitogen Activated Protein Kinase 3 28%
• U0126 28%
• Immunocytochemistry 28%
• Metabolic Pathway 14%
• Ischemia 14%
• Metalloendopeptidase 14%
• Confocal Microscopy 14%
• Glial Cells 14%
• Astrocyte 14%
• Microvessel 14%