@article{1f485e7ad8b643de8f1746da33e32a9c,
title = "Endothelial glycocalyx degradation induces endogenous heparinization in patients with severe injury and early traumatic coagulopathy",
abstract = "There is emerging evidence that early trauma-induced coagulopathy (TIC) is mechanistically linked to disruption of the vascular endothelium and its glycocalyx, assessed by thrombomodulin and syndecan 1, respectively. This study evaluated if degradation of the endothelial glycocalyx and ensuing release of its heparin-like substances induce autoheparinization and thereby contributes to TIC.",
keywords = "Adult, Blood Coagulation Disorders, Blood Transfusion, Endothelium, Vascular, Female, Glycocalyx, Heparin, Humans, Injury Severity Score, Male, Middle Aged, Prospective Studies, Syndecan-1, Thrombelastography, Thrombomodulin, Wounds and Injuries",
author = "Ostrowski, {Sisse R} and Johansson, {P{\"a}r I}",
year = "2012",
doi = "10.1097/TA.0b013e31825b5c10",
language = "English",
volume = "73",
pages = "60--6",
journal = "Journal of Trauma",
issn = "0022-5282",
publisher = "Lippincott Williams and Wilkins",
number = "1",
}