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Endoscopic Ultrasound with Bronchoscope-Guided Fine Needle Aspiration for the Diagnosis of Paraesophageally Located Lung Lesions

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Developing and Gathering Validity Evidence for a Simulation-Based Test of Competencies in Lung Ultrasound

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Development of and Gathering Validity Evidence for a Theoretical Test in Thoracic Ultrasound

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Ensuring Basic Competence in Thoracentesis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. EUS-B-FNA for Diagnosing Liver and Celiac Metastases in Lung Cancer Patients

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Lokalanæstesitorakoskopi ved udredning af recidiverende pleuraeffusion

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Computed tomography of the chest in unilateral pleural effusions: outcome of the British Thoracic Society guideline

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Incidence of malignancy and survival in patients with idiopathic pleuritis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Ensuring Basic Competence in Thoracentesis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. EUS-B-FNA for Diagnosing Liver and Celiac Metastases in Lung Cancer Patients

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: Diagnosing centrally located lung tumors without endobronchial abnormalities and not located near the major airways is a diagnostic challenge. Tumors near or adjacent to the esophagus can be aspirated and detected with esophageal ultrasound (EUS) using gastrointestinal endoscopes.

OBJECTIVE: To assess the feasibility and diagnostic yield of endoscopic ultrasound with bronchoscope-guided fine needle aspiration (EUS-B-FNA) in paraesophageally located lung tumors and its added value to bronchoscopy and endobronchial ultrasound (EBUS).

METHODS: Retrospective, multicenter international study (from January 1, 2015 until January 1, 2018) of patients with suspected lung cancer, undergoing bronchoscopy, EBUS, and endoscopic ultrasound bronchoscopy (EUS-B) in one session by a single operator (pulmonologist), in whom the primary lung tumor was detected and aspirated by EUS-B. In the absence of malignancy following endoscopy, transthoracic ultrasound needle aspiration, clinical and radiological follow-up of at least 6 months was performed. The yield and sensitivity of EUS-B-FNA and its added value to bronchoscopy and EBUS was assessed.

RESULTS: 58 patients were identified with the following diagnosis: non-small-cell lung cancer (n = 43), small-cell lung cancer (n = 6), mesothelioma (n = 2), metastasis (n = 1), nonmalignant (n = 6). The yield and sensitivity of EUS-B-FNA for detecting lung cancer was 90%. In 26 patients (45%), the intrapulmonary tumor was exclusively detected by EUS-B. Adding EUS-B to conventional bronchoscopy and EBUS increased the diagnostic yield for diagnosing lung cancer in para-esophageally located lung tumors from 51 to 91%. No EUS-B-related complications were observed.

CONCLUSION: EUS-B-FNA is a feasible and safe technique for diagnosing centrally located intrapulmonary tumors that are located near or adjacent to the esophagus. EUS-B should be considered in the same endoscopy session following nondiagnostic bronchoscopy and EBUS.

OriginalsprogEngelsk
TidsskriftRespiration; international review of thoracic diseases
Vol/bind97
Udgave nummer4
Sider (fra-til)277-283
Antal sider7
ISSN0025-7931
DOI
StatusUdgivet - 2019

Bibliografisk note

© 2018 The Author(s) Published by S. Karger AG, Basel.

ID: 59294943