Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding

Vibe Frøkjær; David Erritzøe; Anders Juul; Finn Årup Nielsen; Klaus Holst; Claus Svarer; Jacob Madsen; Olaf B Paulson; Gitte M Knudsen

doi:10.1016/j.psyneuen.2010.03.002

Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding

Vibe Frøkjær, David Erritzøe, Anders Juul, Finn Årup Nielsen, Klaus Holst, Claus Svarer, Jacob Madsen, Olaf B Paulson, Gitte M Knudsen

35 Citationer (Scopus)

Abstract

Sex-hormones influence brain function and are likely to play a role in the gender predisposition to mood and anxiety disorders. Acute fluctuations of sex-hormone levels including hormonal replacement therapy appear to affect serotonergic neurotransmission, but it is unknown if baseline levels affect serotonergic neurotransmission. This study was undertaken to examine if baseline levels of endogenous sex hormones are associated with cerebral serotonin 2A (5-HT(2A)) receptor binding in men.

Originalsprog	Engelsk
Tidsskrift	Psychoneuroendocrinology
Vol/bind	35
Udgave nummer	9
Sider (fra-til)	1311-20
Antal sider	10
DOI	https://doi.org/10.1016/j.psyneuen.2010.03.002
Status	Udgivet - 1 okt. 2010

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10.1016/j.psyneuen.2010.03.002

Citationsformater

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title = "Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding",

abstract = "Sex-hormones influence brain function and are likely to play a role in the gender predisposition to mood and anxiety disorders. Acute fluctuations of sex-hormone levels including hormonal replacement therapy appear to affect serotonergic neurotransmission, but it is unknown if baseline levels affect serotonergic neurotransmission. This study was undertaken to examine if baseline levels of endogenous sex hormones are associated with cerebral serotonin 2A (5-HT(2A)) receptor binding in men.",

author = "Vibe Fr{\o}kj{\ae}r and David Erritz{\o}e and Anders Juul and Nielsen, {Finn {\AA}rup} and Klaus Holst and Claus Svarer and Jacob Madsen and Paulson, {Olaf B} and Knudsen, {Gitte M}",

year = "2010",

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doi = "10.1016/j.psyneuen.2010.03.002",

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TY - JOUR

T1 - Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding

AU - Frøkjær, Vibe

AU - Erritzøe, David

AU - Juul, Anders

AU - Nielsen, Finn Årup

AU - Holst, Klaus

AU - Svarer, Claus

AU - Madsen, Jacob

AU - Paulson, Olaf B

AU - Knudsen, Gitte M

PY - 2010/10/1

Y1 - 2010/10/1

N2 - Sex-hormones influence brain function and are likely to play a role in the gender predisposition to mood and anxiety disorders. Acute fluctuations of sex-hormone levels including hormonal replacement therapy appear to affect serotonergic neurotransmission, but it is unknown if baseline levels affect serotonergic neurotransmission. This study was undertaken to examine if baseline levels of endogenous sex hormones are associated with cerebral serotonin 2A (5-HT(2A)) receptor binding in men.

AB - Sex-hormones influence brain function and are likely to play a role in the gender predisposition to mood and anxiety disorders. Acute fluctuations of sex-hormone levels including hormonal replacement therapy appear to affect serotonergic neurotransmission, but it is unknown if baseline levels affect serotonergic neurotransmission. This study was undertaken to examine if baseline levels of endogenous sex hormones are associated with cerebral serotonin 2A (5-HT(2A)) receptor binding in men.

U2 - 10.1016/j.psyneuen.2010.03.002

DO - 10.1016/j.psyneuen.2010.03.002

M3 - Journal article

C2 - 20356681

SN - 1873-3360

VL - 35

SP - 1311

EP - 1320

JO - Psychoneuroendocrinology

JF - Psychoneuroendocrinology

IS - 9

ER -

Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding

Abstract

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