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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Endocrine, metabolic and cardiovascular responses to adrenaline after abdominal surgery

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Vis graf over relationer
Adrenaline-induced changes in heart rate, blood pressure, plasma adrenaline and noradrenaline, cortisol, glucagon, insulin, cAMP, glucose lactate, glycerol and beta-hydroxybutyrate were studied preoperatively and 4 and 24 h after skin incision in 8 patients undergoing elective cholecystectomy. Late postoperative responses of blood glucose, plasma cAMP, lactate and glycerol to adrenaline infusion were reduced, whereas other responses were unaffected. Blood glucose appearance and disappearance rate as assessed by [3H]3-glucose infusion was unchanged pre- and postoperatively. The increase in glucose appearance rate following adrenaline was similar pre- and postoperatively. These findings suggest that several beta-receptor-mediated responses to adrenaline are reduced after abdominal surgery.
OriginalsprogEngelsk
TidsskriftActa Endocrinologica (Copenh)
Vol/bind123
Udgave nummer2
Sider (fra-til)143-8
Antal sider6
ISSN0001-5598
StatusUdgivet - aug. 1990

ID: 40238088