TY - JOUR
T1 - Emotion regulation difficulties in pediatric obsessive-compulsive disorder
T2 - A modifiable treatment target
AU - Thoustrup, Christine Lykke
AU - Olsen, Markus Harboe
AU - Korsbjerg, Nicoline Løcke Jepsen
AU - Ritter, Melanie
AU - Christensen, Sofie Heidenheim
AU - Lønfeldt, Nicole Nadine
AU - Mora-Jensen, Anna Rosa Cecilie
AU - Uhre, Camilla Funch
AU - Uhre, Valdemar Funch
AU - Pretzman, Linea
AU - Gluud, Christian
AU - Engstrøm, Janus
AU - Hagstrøm, Julie
AU - Vangkilde, Signe
AU - Blair, Robert James
AU - Plessen, Kerstin Jessica
AU - Pagsberg, Anne Katrine
N1 - Publisher Copyright:
© 2026 The Authors
PY - 2026/7
Y1 - 2026/7
N2 - Background: Pre-treatment emotion regulation difficulties are extensively reported in pediatric obsessive-compulsive disorder (OCD), yet information regarding whether they are addressed by current interventions and/or moderate treatment outcomes, particularly differentiating between different types of psychotherapy, is lacking. Methods: Seventy-nine adolescents with OCD (11-17 years) completed the Difficulties in Emotion Regulation Scale (DERS) before and after being randomized to 16 weeks of either family-based cognitive behavioral therapy with exposure and response prevention (FCBT) or family-based psychoeducation with relaxation training (FPRT). A cohort of 59 age- and sex-matched adolescents without psychiatric disorders was included to establish temporal stability of emotion regulation and a normative reference level on the DERS. Results: Adolescents in the FCBT group demonstrated post-intervention improvements in emotion regulation, whereas those in the FPRT group did not. Change in OCD symptom severity was neither moderated nor mediated by emotion regulation difficulties in either the FCBT or FPRT group. Sensitivity analyses on treatment completers yielded similar results. Conclusions: The findings confirm emotion regulation difficulties as modifiable targets for psychotherapy in pediatric OCD and suggest that FCBT is effective in improving emotion regulation abilities, while FPRT is not.
AB - Background: Pre-treatment emotion regulation difficulties are extensively reported in pediatric obsessive-compulsive disorder (OCD), yet information regarding whether they are addressed by current interventions and/or moderate treatment outcomes, particularly differentiating between different types of psychotherapy, is lacking. Methods: Seventy-nine adolescents with OCD (11-17 years) completed the Difficulties in Emotion Regulation Scale (DERS) before and after being randomized to 16 weeks of either family-based cognitive behavioral therapy with exposure and response prevention (FCBT) or family-based psychoeducation with relaxation training (FPRT). A cohort of 59 age- and sex-matched adolescents without psychiatric disorders was included to establish temporal stability of emotion regulation and a normative reference level on the DERS. Results: Adolescents in the FCBT group demonstrated post-intervention improvements in emotion regulation, whereas those in the FPRT group did not. Change in OCD symptom severity was neither moderated nor mediated by emotion regulation difficulties in either the FCBT or FPRT group. Sensitivity analyses on treatment completers yielded similar results. Conclusions: The findings confirm emotion regulation difficulties as modifiable targets for psychotherapy in pediatric OCD and suggest that FCBT is effective in improving emotion regulation abilities, while FPRT is not.
KW - Cognitive behavioral therapy
KW - Emotion regulation
KW - Exposure and response prevention
KW - Obsessive-compulsive disorder
KW - Randomized clinical trial
KW - Relaxation training
UR - https://www.scopus.com/pages/publications/105048049943
U2 - 10.1016/j.jocrd.2026.101037
DO - 10.1016/j.jocrd.2026.101037
M3 - Journal article
AN - SCOPUS:105048049943
SN - 2211-3649
VL - 50
JO - Journal of Obsessive-Compulsive and Related Disorders
JF - Journal of Obsessive-Compulsive and Related Disorders
M1 - 101037
ER -