Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate

Henrik Reinhard; Peter R Hansen; Frederik Persson; Lise Tarnow; Niels Wiinberg; Andreas Kjær; Claus L Petersen; Kaj Winther; Hans-Henrik Parving; Peter Rossing; Peter Karl Jacobsen

doi:10.1093/ndt/gfr009

Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate

Henrik Reinhard, Peter R Hansen, Frederik Persson, Lise Tarnow, Niels Wiinberg, Andreas Kjær, Claus L Petersen, Kaj Winther, Hans-Henrik Parving, Peter Rossing, Peter Karl Jacobsen

26 Citationer (Scopus)

Abstract

Elevated plasma N-terminal (NT)-proBNP levels and coronary calcium score (CCS) not only predicts myocardial ischaemia and coronary artery stenosis but also adverse cardiovascular events and mortality in type 2 diabetic patients with an increased urinary albumin excretion rate (UAER), whereas low levels are associated with low frequency of coronary artery disease (CAD) and good prognosis. The underlying causes of poor prognosis in patients with elevated NT-proBNP are not known; thus, we investigated the role of putative asymptomatic CAD in type 2 diabetic patients with UAER >30 mg/24 h and elevated P-NT-proBNP and/or CCS.

Originalsprog	Engelsk
Tidsskrift	Nephrology, Dialysis, Transplantation
Vol/bind	26
Udgave nummer	10
Sider (fra-til)	3242-9
Antal sider	8
ISSN	0931-0509
DOI	https://doi.org/10.1093/ndt/gfr009
Status	Udgivet - 2011

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10.1093/ndt/gfr009

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Reinhard, H., Hansen, P. R., Persson, F., Tarnow, L., Wiinberg, N., Kjær, A., Petersen, C. L., Winther, K., Parving, H.-H., Rossing, P., & Jacobsen, P. K. (2011). Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate. Nephrology, Dialysis, Transplantation, 26(10), 3242-9. https://doi.org/10.1093/ndt/gfr009

Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate. / Reinhard, Henrik; Hansen, Peter R ; Persson, Frederik et al.
I: Nephrology, Dialysis, Transplantation, Bind 26, Nr. 10, 2011, s. 3242-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Reinhard, H, Hansen, PR , Persson, F, Tarnow, L, Wiinberg, N , Kjær, A , Petersen, CL, Winther, K, Parving, H-H , Rossing, P & Jacobsen, PK 2011, 'Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate', Nephrology, Dialysis, Transplantation, bind 26, nr. 10, s. 3242-9. https://doi.org/10.1093/ndt/gfr009

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title = "Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate",

abstract = "Elevated plasma N-terminal (NT)-proBNP levels and coronary calcium score (CCS) not only predicts myocardial ischaemia and coronary artery stenosis but also adverse cardiovascular events and mortality in type 2 diabetic patients with an increased urinary albumin excretion rate (UAER), whereas low levels are associated with low frequency of coronary artery disease (CAD) and good prognosis. The underlying causes of poor prognosis in patients with elevated NT-proBNP are not known; thus, we investigated the role of putative asymptomatic CAD in type 2 diabetic patients with UAER >30 mg/24 h and elevated P-NT-proBNP and/or CCS.",

author = "Henrik Reinhard and Hansen, {Peter R} and Frederik Persson and Lise Tarnow and Niels Wiinberg and Andreas Kj{\ae}r and Petersen, {Claus L} and Kaj Winther and Hans-Henrik Parving and Peter Rossing and Jacobsen, {Peter Karl}",

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doi = "10.1093/ndt/gfr009",

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AU - Reinhard, Henrik

AU - Hansen, Peter R

AU - Persson, Frederik

AU - Tarnow, Lise

AU - Wiinberg, Niels

AU - Kjær, Andreas

AU - Petersen, Claus L

AU - Winther, Kaj

AU - Parving, Hans-Henrik

AU - Rossing, Peter

AU - Jacobsen, Peter Karl

PY - 2011

Y1 - 2011

N2 - Elevated plasma N-terminal (NT)-proBNP levels and coronary calcium score (CCS) not only predicts myocardial ischaemia and coronary artery stenosis but also adverse cardiovascular events and mortality in type 2 diabetic patients with an increased urinary albumin excretion rate (UAER), whereas low levels are associated with low frequency of coronary artery disease (CAD) and good prognosis. The underlying causes of poor prognosis in patients with elevated NT-proBNP are not known; thus, we investigated the role of putative asymptomatic CAD in type 2 diabetic patients with UAER >30 mg/24 h and elevated P-NT-proBNP and/or CCS.

AB - Elevated plasma N-terminal (NT)-proBNP levels and coronary calcium score (CCS) not only predicts myocardial ischaemia and coronary artery stenosis but also adverse cardiovascular events and mortality in type 2 diabetic patients with an increased urinary albumin excretion rate (UAER), whereas low levels are associated with low frequency of coronary artery disease (CAD) and good prognosis. The underlying causes of poor prognosis in patients with elevated NT-proBNP are not known; thus, we investigated the role of putative asymptomatic CAD in type 2 diabetic patients with UAER >30 mg/24 h and elevated P-NT-proBNP and/or CCS.

U2 - 10.1093/ndt/gfr009

DO - 10.1093/ndt/gfr009

M3 - Journal article

C2 - 21372253

SN - 0931-0509

VL - 26

SP - 3242

EP - 3249

JO - Nephrology, Dialysis, Transplantation

JF - Nephrology, Dialysis, Transplantation

IS - 10

ER -

Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate

Abstract

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