TY - JOUR
T1 - Efficacy of 10-20-30 training versus moderate-intensity continuous training on HbA1c, body composition and maximum oxygen uptake in male patients with type 2 diabetes
T2 - A randomized controlled trial
AU - Baasch-Skytte, Thomas
AU - Lemgart, Charlotte T
AU - Oehlenschläger, Mads H
AU - Petersen, Pernille E
AU - Hostrup, Morten
AU - Bangsbo, Jens
AU - Gunnarsson, Thomas P
N1 - © 2020 John Wiley & Sons Ltd.
PY - 2020/5/1
Y1 - 2020/5/1
N2 - Aim: To compare the efficacy of 10-20-30 training versus moderate-intensity continuous training (MICT) on HbA1c, body composition and maximum oxygen uptake (V˙O
2max) in male patients with type 2 diabetes (T2D). Materials and Methods: Fifty-one male participants with T2D were randomly assigned (1:1) to a 10-20-30 (N = 26) and a MICT (N = 25) training group. Interventions consisted of supervised cycling three times weekly for 10 weeks, lasting 29 minutes (10-20-30) and 50 minutes (MICT) in a local non-clinical setting. The primary outcome was change in HbA1c from baseline to 10-week follow-up. Results: Of 51 participants enrolled, 44 (mean age 61.0 ± 6.8 [mean ± SD] years, diagnosed 7.5 ± 5.8 years, baseline HbA1c 7.4% ± 1.3%) were included in the analysis. Training compliance was 84% and 86% in 10-20-30 and MICT, respectively. No adverse events occurred during the intervention. HbA1c decreased (P <0.001) by 0.5 (95% CI −0.72 to −0.21) percentage points with training in 10-20-30, with no change in MICT. The change in 10-20-30 was greater (P <0.05) than in MICT. Visceral fat mass decreased (P <0.05) only with 10-20-30 training, whereas total fat mass decreased (P <0.01) and V˙O
2max increased (P <0.01) with training in both groups. Conclusions: Ten weeks of 10-20-30 training was superior to MICT in lowering HbA1c, and only 10-20-30 training decreased visceral fat mass in patients with T2D. Furthermore, 10-20-30 training was as effective as MICT in reducing total fat mass and increasing V˙O
2max, despite a 42% lower training time commitment.
AB - Aim: To compare the efficacy of 10-20-30 training versus moderate-intensity continuous training (MICT) on HbA1c, body composition and maximum oxygen uptake (V˙O
2max) in male patients with type 2 diabetes (T2D). Materials and Methods: Fifty-one male participants with T2D were randomly assigned (1:1) to a 10-20-30 (N = 26) and a MICT (N = 25) training group. Interventions consisted of supervised cycling three times weekly for 10 weeks, lasting 29 minutes (10-20-30) and 50 minutes (MICT) in a local non-clinical setting. The primary outcome was change in HbA1c from baseline to 10-week follow-up. Results: Of 51 participants enrolled, 44 (mean age 61.0 ± 6.8 [mean ± SD] years, diagnosed 7.5 ± 5.8 years, baseline HbA1c 7.4% ± 1.3%) were included in the analysis. Training compliance was 84% and 86% in 10-20-30 and MICT, respectively. No adverse events occurred during the intervention. HbA1c decreased (P <0.001) by 0.5 (95% CI −0.72 to −0.21) percentage points with training in 10-20-30, with no change in MICT. The change in 10-20-30 was greater (P <0.05) than in MICT. Visceral fat mass decreased (P <0.05) only with 10-20-30 training, whereas total fat mass decreased (P <0.01) and V˙O
2max increased (P <0.01) with training in both groups. Conclusions: Ten weeks of 10-20-30 training was superior to MICT in lowering HbA1c, and only 10-20-30 training decreased visceral fat mass in patients with T2D. Furthermore, 10-20-30 training was as effective as MICT in reducing total fat mass and increasing V˙O
2max, despite a 42% lower training time commitment.
KW - glycaemic control
KW - high-intensity interval training
KW - oral glucose tolerance test
KW - skeletal muscle protein adaptations
KW - sprint-interval training.
UR - http://www.scopus.com/inward/record.url?scp=85078667025&partnerID=8YFLogxK
U2 - 10.1111/dom.13953
DO - 10.1111/dom.13953
M3 - Journal article
C2 - 31903682
SN - 1462-8902
VL - 22
SP - 767
EP - 778
JO - Diabetes, Obesity and Metabolism
JF - Diabetes, Obesity and Metabolism
IS - 5
ER -