TY - JOUR
T1 - Efficacy and safety of TNF-α inhibitors in refractory primary complex aphthosis
T2 - a patient series and overview of the literature
AU - Sand, Freja Lærke
AU - Thomsen, Simon Francis
PY - 2013/12
Y1 - 2013/12
N2 - Otherwise healthy patients with severe recurrent mucocutaneous aphthous ulcerations (complex aphthosis) may require systemic immunomodulatory therapy. However, a subset of patients remain resistant or intolerant to recommended therapeutic agents. Recently, case reports have described that tumor necrosis factor-α (TNF-α) inhibitors may induce remission in these patients.
AB - Otherwise healthy patients with severe recurrent mucocutaneous aphthous ulcerations (complex aphthosis) may require systemic immunomodulatory therapy. However, a subset of patients remain resistant or intolerant to recommended therapeutic agents. Recently, case reports have described that tumor necrosis factor-α (TNF-α) inhibitors may induce remission in these patients.
U2 - 10.3109/09546634.2013.800633
DO - 10.3109/09546634.2013.800633
M3 - Journal article
C2 - 23621315
SN - 0954-6634
VL - 24
SP - 444
EP - 446
JO - The Journal of dermatological treatment
JF - The Journal of dermatological treatment
IS - 6
ER -