Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Effects of thoracic paravertebral block with bupivacaine versus combined thoracic epidural block with bupivacaine and morphine on pain and pulmonary function after cholecystectomy.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskning

  1. Hypothermic to ischemic ratio and mortality in post-cardiac arrest patients

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Response letter to comments made by J. G. Förster, M. Pitkänen

    Publikation: Bidrag til tidsskriftLetterForskningpeer review

  3. APACHE II score validation in emergency abdominal surgery. A post hoc analysis of the InCare trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • D Bigler
  • W Dirkes
  • R Hansen
  • J Rosenberg
  • H Kehlet
Vis graf over relationer
Twenty patients undergoing elective cholecystectomy via a subcostal incision were randomized in a double-blind study to either thoracic paravertebral blockade with bupivacaine 0.5% (15 ml followed by 5 ml/h) or thoracic epidural blockade with bupivacaine 7 ml 0.5% + morphine 2 mg followed by 5 ml/h + 0.2 mg/h, respectively for 8 h postoperatively. Mean initial spread of sensory analgesia on the right side was the same (Th3,4-Th11 versus Th2,6-Th11), but decreased (P less than 0.05) postoperatively in the paravertebral group. All patients in the epidural group had bilateral blockade, compared with three patients in the paravertebral group. In both groups only minor insignificant changes in blood pressure and pulse rate were seen postoperatively. Pain scores were significantly higher in the paravertebral group, as was the need for systemic morphine (P less than 0.05). Pulmonary function estimated by forced vital capacity, forced expiratory volume and peak expiratory flow rate decreased about 50% postoperatively in both groups. In conclusion, the continuous paravertebral bupivacaine infusion used here was insufficient as the only analgesic after cholecystectomy. In contrast, epidural blockade with combined bupivacaine and low dose morphine produced total pain relief in six of ten patients.
Bidragets oversatte titelEffects of thoracic paravertebral block with bupivacaine versus combined thoracic epidural block with bupivacaine and morphine on pain and pulmonary function after cholecystectomy.
OriginalsprogEngelsk
TidsskriftActa Anaesthesiologica Scandinavica
Vol/bind33
Udgave nummer7
Sider (fra-til)561-564
Antal sider4
ISSN0001-5172
StatusUdgivet - 1989

ID: 32503624