@article{95dbd020f81b4235b1da53e19dd2e2b0,
title = "Effects of insulin detemir and NPH insulin on renal handling of sodium, fluid retention and weight in type 2 diabetic patients",
abstract = "In type 2 diabetic patients, insulin detemir (B29Lys(ε-tetradecanoyl),desB30 human insulin) induces less weight gain than NPH insulin. Due to the proposed reduction of tubular action by insulin detemir, type 2 diabetic patients should have increased urinary sodium excretion, thereby reducing extracellular volume and body weight when changed from NPH insulin to insulin detemir.",
keywords = "Aged, Body Composition, Cross-Over Studies, Diabetes Mellitus, Type 2, Extracellular Fluid, Fluid Shifts, Glomerular Filtration Rate, Humans, Hypoglycemic Agents, Insulin, Isophane, Insulin, Long-Acting, Insulin, Regular, Human, Middle Aged, Outpatient Clinics, Hospital, Patient Dropouts, Sodium, Time Factors, Water-Electrolyte Balance, Weight Loss",
author = "Hendriksen, {K V} and Jensen, {Tonny Joran} and P Oturai and B Feldt-Rasmussen",
year = "2012",
doi = "10.1007/s00125-011-2345-8",
language = "English",
volume = "55",
pages = "46--50",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer Science and Business Media Deutschland GmbH",
number = "1",
}