Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Effects of active commuting and leisure-time exercise on appetite in individuals with overweight and obesity

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Harvard

Quist, JS, Blond, MB, Gram, AS, Steenholt, CB, Janus, C, Holst, JJ, Rehfeld, JF, Sjödin, A, Stallknecht, B & Rosenkilde, M 2019, 'Effects of active commuting and leisure-time exercise on appetite in individuals with overweight and obesity' Journal of Applied Physiology, bind 126, nr. 4, s. 941-951. https://doi.org/10.1152/japplphysiol.00239.2018

APA

Quist, J. S., Blond, M. B., Gram, A. S., Steenholt, C. B., Janus, C., Holst, J. J., ... Rosenkilde, M. (2019). Effects of active commuting and leisure-time exercise on appetite in individuals with overweight and obesity. Journal of Applied Physiology, 126(4), 941-951. https://doi.org/10.1152/japplphysiol.00239.2018

CBE

MLA

Vancouver

Author

Quist, Jonas Salling ; Blond, Martin Bæk ; Gram, Anne Sofie ; Steenholt, Carina Bjørnskov ; Janus, Charlotte ; Holst, Jens Juul ; Rehfeld, Jens F ; Sjödin, Anders ; Stallknecht, Bente ; Rosenkilde, Mads. / Effects of active commuting and leisure-time exercise on appetite in individuals with overweight and obesity. I: Journal of Applied Physiology. 2019 ; Bind 126, Nr. 4. s. 941-951.

Bibtex

@article{aca2826639634f7dbfc5d50ee1737c46,
title = "Effects of active commuting and leisure-time exercise on appetite in individuals with overweight and obesity",
abstract = "Acute exercise is associated with a transient suppression of appetite. The effects of regular exercise on appetite are not well understood. We aimed to determine the effects of active commuting and leisure-time exercise on appetite. One hundred thirty physically inactive women and men (20-45 yr) with overweight and obesity were randomized to 6 mo of habitual lifestyle (CON, n = 18), active commuting (BIKE, n = 35), or leisure-time exercise of moderate [MOD, 50{\%} peak oxygen uptake (V̇o2peak)-reserve, n = 39] or vigorous (VIG, 70{\%} V̇o2peak-reserve, n = 38) intensity. Appetite ratings, acylated ghrelin, cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), peptide YY (PYY), and glucagon were assessed in the basal state and in response to meal and exercise challenges at baseline and 3 and 6 mo. Ad libitum energy intake was determined during test meals. Data from 90 participants (per protocol) were available, and results are comparisons with CON. At 3 mo, ad libitum energy intake was lower in VIG (-22{\%}, P < 0.01), basal glucagon was lower in BIKE ( P < 0.05) and VIG ( P = 0.01), and postprandial ratings of prospective food consumption were lower in MOD ( P = 0.02) and VIG ( P < 0.001). In VIG, ratings of hunger ( P = 0.01) and prospective food consumption ( P = 0.03) were lower after acute exercise at 3 mo. At 6 mo, basal and postprandial GLP-1 were higher ( P ≤ 0.04) whereas postexercise PYY was lower ( P = 0.03) in VIG and postexercise CCK was lower in BIKE ( P = 0.03). Vigorous-intensity exercise training leads to a transient suppression of energy intake and subjective appetite (3 mo) but a more long-term increase in basal and postprandial GLP-1 (6 mo) in individuals with overweight and obesity. NEW & NOTEWORTHY This is the first randomized controlled trial, to our knowledge, investigating long-term effects of exercise domain and intensity on subjective and hormonal markers of appetite and ad libitum energy intake in individuals with overweight and obesity. Appetite was assessed in response to meal and exercise challenges at baseline and at 3 and 6 mo. Anorexigenic effects of exercise vary with the duration of intervention and are restricted to regular leisure-time exercise of vigorous intensity in individuals with overweight and obesity.",
author = "Quist, {Jonas Salling} and Blond, {Martin B{\ae}k} and Gram, {Anne Sofie} and Steenholt, {Carina Bj{\o}rnskov} and Charlotte Janus and Holst, {Jens Juul} and Rehfeld, {Jens F} and Anders Sj{\"o}din and Bente Stallknecht and Mads Rosenkilde",
year = "2019",
month = "4",
day = "1",
doi = "10.1152/japplphysiol.00239.2018",
language = "English",
volume = "126",
pages = "941--951",
journal = "Journal of Applied Physiology",
issn = "0161-7567",
publisher = "American Physiological Society",
number = "4",

}

RIS

TY - JOUR

T1 - Effects of active commuting and leisure-time exercise on appetite in individuals with overweight and obesity

AU - Quist, Jonas Salling

AU - Blond, Martin Bæk

AU - Gram, Anne Sofie

AU - Steenholt, Carina Bjørnskov

AU - Janus, Charlotte

AU - Holst, Jens Juul

AU - Rehfeld, Jens F

AU - Sjödin, Anders

AU - Stallknecht, Bente

AU - Rosenkilde, Mads

PY - 2019/4/1

Y1 - 2019/4/1

N2 - Acute exercise is associated with a transient suppression of appetite. The effects of regular exercise on appetite are not well understood. We aimed to determine the effects of active commuting and leisure-time exercise on appetite. One hundred thirty physically inactive women and men (20-45 yr) with overweight and obesity were randomized to 6 mo of habitual lifestyle (CON, n = 18), active commuting (BIKE, n = 35), or leisure-time exercise of moderate [MOD, 50% peak oxygen uptake (V̇o2peak)-reserve, n = 39] or vigorous (VIG, 70% V̇o2peak-reserve, n = 38) intensity. Appetite ratings, acylated ghrelin, cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), peptide YY (PYY), and glucagon were assessed in the basal state and in response to meal and exercise challenges at baseline and 3 and 6 mo. Ad libitum energy intake was determined during test meals. Data from 90 participants (per protocol) were available, and results are comparisons with CON. At 3 mo, ad libitum energy intake was lower in VIG (-22%, P < 0.01), basal glucagon was lower in BIKE ( P < 0.05) and VIG ( P = 0.01), and postprandial ratings of prospective food consumption were lower in MOD ( P = 0.02) and VIG ( P < 0.001). In VIG, ratings of hunger ( P = 0.01) and prospective food consumption ( P = 0.03) were lower after acute exercise at 3 mo. At 6 mo, basal and postprandial GLP-1 were higher ( P ≤ 0.04) whereas postexercise PYY was lower ( P = 0.03) in VIG and postexercise CCK was lower in BIKE ( P = 0.03). Vigorous-intensity exercise training leads to a transient suppression of energy intake and subjective appetite (3 mo) but a more long-term increase in basal and postprandial GLP-1 (6 mo) in individuals with overweight and obesity. NEW & NOTEWORTHY This is the first randomized controlled trial, to our knowledge, investigating long-term effects of exercise domain and intensity on subjective and hormonal markers of appetite and ad libitum energy intake in individuals with overweight and obesity. Appetite was assessed in response to meal and exercise challenges at baseline and at 3 and 6 mo. Anorexigenic effects of exercise vary with the duration of intervention and are restricted to regular leisure-time exercise of vigorous intensity in individuals with overweight and obesity.

AB - Acute exercise is associated with a transient suppression of appetite. The effects of regular exercise on appetite are not well understood. We aimed to determine the effects of active commuting and leisure-time exercise on appetite. One hundred thirty physically inactive women and men (20-45 yr) with overweight and obesity were randomized to 6 mo of habitual lifestyle (CON, n = 18), active commuting (BIKE, n = 35), or leisure-time exercise of moderate [MOD, 50% peak oxygen uptake (V̇o2peak)-reserve, n = 39] or vigorous (VIG, 70% V̇o2peak-reserve, n = 38) intensity. Appetite ratings, acylated ghrelin, cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), peptide YY (PYY), and glucagon were assessed in the basal state and in response to meal and exercise challenges at baseline and 3 and 6 mo. Ad libitum energy intake was determined during test meals. Data from 90 participants (per protocol) were available, and results are comparisons with CON. At 3 mo, ad libitum energy intake was lower in VIG (-22%, P < 0.01), basal glucagon was lower in BIKE ( P < 0.05) and VIG ( P = 0.01), and postprandial ratings of prospective food consumption were lower in MOD ( P = 0.02) and VIG ( P < 0.001). In VIG, ratings of hunger ( P = 0.01) and prospective food consumption ( P = 0.03) were lower after acute exercise at 3 mo. At 6 mo, basal and postprandial GLP-1 were higher ( P ≤ 0.04) whereas postexercise PYY was lower ( P = 0.03) in VIG and postexercise CCK was lower in BIKE ( P = 0.03). Vigorous-intensity exercise training leads to a transient suppression of energy intake and subjective appetite (3 mo) but a more long-term increase in basal and postprandial GLP-1 (6 mo) in individuals with overweight and obesity. NEW & NOTEWORTHY This is the first randomized controlled trial, to our knowledge, investigating long-term effects of exercise domain and intensity on subjective and hormonal markers of appetite and ad libitum energy intake in individuals with overweight and obesity. Appetite was assessed in response to meal and exercise challenges at baseline and at 3 and 6 mo. Anorexigenic effects of exercise vary with the duration of intervention and are restricted to regular leisure-time exercise of vigorous intensity in individuals with overweight and obesity.

U2 - 10.1152/japplphysiol.00239.2018

DO - 10.1152/japplphysiol.00239.2018

M3 - Journal article

VL - 126

SP - 941

EP - 951

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 0161-7567

IS - 4

ER -

ID: 57231148