TY - JOUR
T1 - Effects of a screening and treatment protocol with haloperidol on post-cardiotomy delirium
T2 - a prospective cohort study
AU - Schrøder Pedersen, Sofie
AU - Kirkegaard, Thomas
AU - Balslev Jørgensen, Martin
AU - Jørgensen, Vibeke Renée Lind
PY - 2014/4
Y1 - 2014/4
N2 - Post-cardiotomy delirium is common and associated with increased morbidity and mortality. No gold standard exists for detecting delirium, and evidence to support the choice of treatment is needed. Haloperidol is widely used for treating delirium, but indication, doses and therapeutic targets vary. Moreover, doubt has been raised regarding overall efficacy. The purpose of this study was to assess the effect of a combination of early detection and standardized treatment with haloperidol on post-cardiotomy delirium, with the hypothesis that the proportion of delirium- and coma-free days could be increased. Length of stay (LOS), complications and 180-day mortality are reported.
AB - Post-cardiotomy delirium is common and associated with increased morbidity and mortality. No gold standard exists for detecting delirium, and evidence to support the choice of treatment is needed. Haloperidol is widely used for treating delirium, but indication, doses and therapeutic targets vary. Moreover, doubt has been raised regarding overall efficacy. The purpose of this study was to assess the effect of a combination of early detection and standardized treatment with haloperidol on post-cardiotomy delirium, with the hypothesis that the proportion of delirium- and coma-free days could be increased. Length of stay (LOS), complications and 180-day mortality are reported.
U2 - 10.1093/icvts/ivt501
DO - 10.1093/icvts/ivt501
M3 - Journal article
C2 - 24357472
SN - 1010-7940
VL - 18
SP - 438
EP - 445
JO - European Journal of Cardio-thoracic Surgery
JF - European Journal of Cardio-thoracic Surgery
IS - 4
ER -