Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study

Linda Wittkop, Huldrych F Günthard, Frank de Wolf, David Dunn, Alessandro Cozzi-Lepri, Andrea de Luca, Claudia Kücherer, Niels Obel, Viktor von Wyl, Bernard Masquelier, Christoph Stephan, Carlo Torti, Andrea Antinori, Federico García, Ali Judd, Kholoud Porter, Rodolphe Thiébaut, Hannah Castro, Ard I van Sighem, Céline ColinJesper Kjaer, Jens D Lundgren, Roger Paredes, Anton Pozniak, Bonaventura Clotet, Andrew Phillips, Deenan Pillay, Geneviève Chêne, EuroCoord-CHAIN study group

    348 Citationer (Scopus)

    Abstract

    The effect of transmitted drug resistance (TDR) on first-line combination antiretroviral therapy (cART) for HIV-1 needs further study to inform choice of optimum drug regimens. We investigated the effect of TDR on outcome in the first year of cART within a large European collaboration.
    OriginalsprogEngelsk
    TidsskriftLancet Infectious Diseases
    Vol/bind11
    Udgave nummer5
    Sider (fra-til)363-71
    Antal sider9
    ISSN1473-3099
    DOI
    StatusUdgivet - 1 maj 2011

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