@article{5e430f904bc74cb2b4fbebd9d6e765c7,
title = "Effect of the direct renin inhibitor aliskiren on left ventricular remodelling following myocardial infarction with systolic dysfunction",
abstract = "Direct renin inhibitors provide an alternative approach to inhibiting the renin-angiotensin-aldosterone system (RAAS) at the most proximal, specific, and rate-limiting step. We tested the hypothesis that direct renin inhibition would attenuate left ventricular remodelling in patients following acute myocardial infarction receiving stable, individually optimized therapy, including another inhibitor of the RAAS.",
keywords = "Aged, Amides, Blood Pressure, Cardiotonic Agents, Death, Sudden, Cardiac, Female, Fumarates, Hospitalization, Humans, Male, Middle Aged, Myocardial Infarction, Recurrence, Renin, Systole, Treatment Outcome, Ventricular Dysfunction, Left, Ventricular Remodeling",
author = "Solomon, {Scott D} and Shin, {Sung Hee} and Amil Shah and Hicham Skali and Akshay Desai and Lars Kober and Maggioni, {Aldo P} and Rouleau, {Jean L} and Kelly, {Roxzana Y} and Allen Hester and McMurray, {John J V} and Pfeffer, {Marc A} and {Aliskiren Study in Post-MI Patients to Reduce Remodeling (ASPIRE) Investigators}",
year = "2011",
doi = "10.1093/eurheartj/ehq522",
language = "English",
volume = "32",
pages = "1227--34",
journal = "European Heart Journal (English Edition)",
issn = "0195-668X",
publisher = "Oxford University Press",
number = "10",
}