Effect of sex, age, and race on the clinical presentation of tuberculosis: a 15-year population-based study

Xinyu Zhang, Aase B Andersen, Troels Lillebaek, Zaza Kamper-Jørgensen, Vibeke Østergaard Thomsen, Karin Ladefoged, Carl F Marrs, Lixin Zhang, Zhenhua Yang

    45 Citationer (Scopus)

    Abstract

    Extrapulmonary tuberculosis (EPTB) is an important health problem that may cause serious morbidity and diagnostic challenges. We conducted a case-control study involving 5,684, approximately 99% of bacteriologically confirmed TB patients (including 1,925 EPTB cases) diagnosed in Denmark and Greenland during 1992-2007 to gain insight to the role of host factors in EPTB pathogenesis. Among patients from Somalia and Asia, persons 25-44 and 45-64 years of age were more likely to have EPTB than persons 15-24 years of age. In contrast, among persons from Greenland, the two oldest age groups were significantly less likely to have EPTB than the youngest age group. For all the age groups, the odds for having EPTB was significantly higher among patients from Somalia and Asia and significantly lower among the patients from Greenland than among patients from Denmark. Furthermore, the occurrence of specific types of EPTB significantly varied among different age groups or origins.
    OriginalsprogEngelsk
    TidsskriftAmerican Journal of Tropical Medicine and Hygiene
    Vol/bind85
    Udgave nummer2
    Sider (fra-til)285-90
    Antal sider6
    ISSN0002-9637
    DOI
    StatusUdgivet - 2011

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