Effect of pamidronate 30 mg versus 90 mg on physical function in patients with newly diagnosed multiple myeloma (Nordic Myeloma Study Group): a double-blind, randomised controlled trial

Peter Gimsing; Kristina Carlson; Ingemar Turesson; Peter Fayers; Anders Waage; Annette Vangsted; Anne Mylin; Christian Gluud; Gunnar Juliusson; Henrik Gregersen; Henrik Hjorth-Hansen; Ingerid Nesthus; Inger Marie Dahl Bahn; Jan Westin; Johan Lanng Nielsen; Lene Meldgaard Knudsen; Lucia Ahlberg; Martin Hjorth; Niels Abildgaard; Niels Frost Andersen; Olle Linder; Finn Wisløff

doi:10.1016/S1470-2045(10)70198-4

Effect of pamidronate 30 mg versus 90 mg on physical function in patients with newly diagnosed multiple myeloma (Nordic Myeloma Study Group): a double-blind, randomised controlled trial

Peter Gimsing, Kristina Carlson, Ingemar Turesson, Peter Fayers, Anders Waage, Annette Vangsted, Anne Mylin, Christian Gluud, Gunnar Juliusson, Henrik Gregersen, Henrik Hjorth-Hansen, Ingerid Nesthus, Inger Marie Dahl Bahn, Jan Westin, Johan Lanng Nielsen, Lene Meldgaard Knudsen, Lucia Ahlberg, Martin Hjorth, Niels Abildgaard, Niels Frost AndersenOlle Linder, Finn Wisløff

Copenhagen Trial Unit Rigshospitalet

108 Citationer (Scopus)

Abstract

Compared with placebo, prophylactic treatment with bisphosphonates reduces risk of skeletal events in patients with multiple myeloma. However, because of toxicity associated with long-term bisphosphonate treatment, establishing the lowest effective dose is important. This study compared the effect of two doses of pamidronate on health-related quality of life and skeletal morbidity in patients with newly diagnosed multiple myeloma.

Originalsprog	Engelsk
Tidsskrift	Lancet Oncology
Vol/bind	11
Udgave nummer	10
Sider (fra-til)	973-82
Antal sider	10
DOI	https://doi.org/10.1016/S1470-2045(10)70198-4
Status	Udgivet - 1 okt. 2010

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10.1016/S1470-2045(10)70198-4

Citationsformater

Gimsing, P., Carlson, K., Turesson, I., Fayers, P., Waage, A., Vangsted, A., Mylin, A., Gluud, C., Juliusson, G., Gregersen, H., Hjorth-Hansen, H., Nesthus, I., Bahn, I. M. D., Westin, J., Nielsen, J. L., Meldgaard Knudsen, L., Ahlberg, L., Hjorth, M., Abildgaard, N., ... Wisløff, F. (2010). Effect of pamidronate 30 mg versus 90 mg on physical function in patients with newly diagnosed multiple myeloma (Nordic Myeloma Study Group): a double-blind, randomised controlled trial. Lancet Oncology, 11(10), 973-82. https://doi.org/10.1016/S1470-2045(10)70198-4

Effect of pamidronate 30 mg versus 90 mg on physical function in patients with newly diagnosed multiple myeloma (Nordic Myeloma Study Group): a double-blind, randomised controlled trial. / Gimsing, Peter; Carlson, Kristina; Turesson, Ingemar et al.
I: Lancet Oncology, Bind 11, Nr. 10, 01.10.2010, s. 973-82.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Gimsing, P, Carlson, K, Turesson, I, Fayers, P, Waage, A, Vangsted, A , Mylin, A , Gluud, C, Juliusson, G, Gregersen, H, Hjorth-Hansen, H, Nesthus, I, Bahn, IMD, Westin, J, Nielsen, JL, Meldgaard Knudsen, L, Ahlberg, L, Hjorth, M, Abildgaard, N, Andersen, NF, Linder, O & Wisløff, F 2010, 'Effect of pamidronate 30 mg versus 90 mg on physical function in patients with newly diagnosed multiple myeloma (Nordic Myeloma Study Group): a double-blind, randomised controlled trial', Lancet Oncology, bind 11, nr. 10, s. 973-82. https://doi.org/10.1016/S1470-2045(10)70198-4

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abstract = "Compared with placebo, prophylactic treatment with bisphosphonates reduces risk of skeletal events in patients with multiple myeloma. However, because of toxicity associated with long-term bisphosphonate treatment, establishing the lowest effective dose is important. This study compared the effect of two doses of pamidronate on health-related quality of life and skeletal morbidity in patients with newly diagnosed multiple myeloma.",

author = "Peter Gimsing and Kristina Carlson and Ingemar Turesson and Peter Fayers and Anders Waage and Annette Vangsted and Anne Mylin and Christian Gluud and Gunnar Juliusson and Henrik Gregersen and Henrik Hjorth-Hansen and Ingerid Nesthus and Bahn, {Inger Marie Dahl} and Jan Westin and Nielsen, {Johan Lanng} and {Meldgaard Knudsen}, Lene and Lucia Ahlberg and Martin Hjorth and Niels Abildgaard and Andersen, {Niels Frost} and Olle Linder and Finn Wisl{\o}ff",

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doi = "10.1016/S1470-2045(10)70198-4",

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AU - Turesson, Ingemar

AU - Fayers, Peter

AU - Waage, Anders

AU - Vangsted, Annette

AU - Mylin, Anne

AU - Gluud, Christian

AU - Juliusson, Gunnar

AU - Gregersen, Henrik

AU - Hjorth-Hansen, Henrik

AU - Nesthus, Ingerid

AU - Bahn, Inger Marie Dahl

AU - Westin, Jan

AU - Nielsen, Johan Lanng

AU - Meldgaard Knudsen, Lene

AU - Ahlberg, Lucia

AU - Hjorth, Martin

AU - Abildgaard, Niels

AU - Andersen, Niels Frost

AU - Linder, Olle

AU - Wisløff, Finn

PY - 2010/10/1

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N2 - Compared with placebo, prophylactic treatment with bisphosphonates reduces risk of skeletal events in patients with multiple myeloma. However, because of toxicity associated with long-term bisphosphonate treatment, establishing the lowest effective dose is important. This study compared the effect of two doses of pamidronate on health-related quality of life and skeletal morbidity in patients with newly diagnosed multiple myeloma.

AB - Compared with placebo, prophylactic treatment with bisphosphonates reduces risk of skeletal events in patients with multiple myeloma. However, because of toxicity associated with long-term bisphosphonate treatment, establishing the lowest effective dose is important. This study compared the effect of two doses of pamidronate on health-related quality of life and skeletal morbidity in patients with newly diagnosed multiple myeloma.

U2 - 10.1016/S1470-2045(10)70198-4

DO - 10.1016/S1470-2045(10)70198-4

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SN - 1474-5488

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JO - Lancet Oncology

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ER -

Effect of pamidronate 30 mg versus 90 mg on physical function in patients with newly diagnosed multiple myeloma (Nordic Myeloma Study Group): a double-blind, randomised controlled trial

Abstract

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