Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice; impact of PGC-1α

Stine Ringholm, Jesper Olesen, Jesper Thorhauge Pedersen, Christina Tingbjerg Brandt, Jens Frey Halling, Ylva Hellsten, Clara Prats, Henriette Pilegaard

    53 Citationer (Scopus)

    Abstract

    The present study tested the hypothesis that lifelong resveratrol (RSV) supplementation counteracts an age-associated decrease in skeletal muscle oxidative capacity through peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α and that RSV combined with lifelong exercise training (EX) exerts additive effects through PGC-1α in mice.
    OriginalsprogEngelsk
    TidsskriftExperimental Gerontology
    Vol/bind48
    Udgave nummer11
    Sider (fra-til)1311-8
    Antal sider8
    ISSN0531-5565
    DOI
    StatusUdgivet - nov. 2013

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