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Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats

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@article{bee52b32b0d54bd781ab6b07e85a2189,
title = "Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats",
abstract = "PTH increases ionic calcium concentration in the serum, acting primarily on bone and kidney cells through the type 1 PTH receptor. Interestingly, PTH stimulates bone formation when administrated intermittently but causes severe bone loss with continuous administration. Daily injections of PTH are used as the most promising anabolic agent in the treatment of severe osteoporosis. Elevated PTH is reported an independent risk factor for left ventricle hypertrophy.",
author = "Sanela Smajilovic and Rasmus Schaal-Jensen and Reza Jabbari and Una Smajilovic and Stig Haunso and Jacob Tfelt-Hansen",
year = "2010",
month = "1",
day = "1",
doi = "10.2174/1874192401004010110",
language = "English",
volume = "4",
pages = "110--6",
journal = "The Open Cardiovascular Medicine Journal",
issn = "1874-1924",
publisher = "Bentham Open",

}

RIS

TY - JOUR

T1 - Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats

AU - Smajilovic, Sanela

AU - Schaal-Jensen, Rasmus

AU - Jabbari, Reza

AU - Smajilovic, Una

AU - Haunso, Stig

AU - Tfelt-Hansen, Jacob

PY - 2010/1/1

Y1 - 2010/1/1

N2 - PTH increases ionic calcium concentration in the serum, acting primarily on bone and kidney cells through the type 1 PTH receptor. Interestingly, PTH stimulates bone formation when administrated intermittently but causes severe bone loss with continuous administration. Daily injections of PTH are used as the most promising anabolic agent in the treatment of severe osteoporosis. Elevated PTH is reported an independent risk factor for left ventricle hypertrophy.

AB - PTH increases ionic calcium concentration in the serum, acting primarily on bone and kidney cells through the type 1 PTH receptor. Interestingly, PTH stimulates bone formation when administrated intermittently but causes severe bone loss with continuous administration. Daily injections of PTH are used as the most promising anabolic agent in the treatment of severe osteoporosis. Elevated PTH is reported an independent risk factor for left ventricle hypertrophy.

U2 - 10.2174/1874192401004010110

DO - 10.2174/1874192401004010110

M3 - Journal article

VL - 4

SP - 110

EP - 116

JO - The Open Cardiovascular Medicine Journal

JF - The Open Cardiovascular Medicine Journal

SN - 1874-1924

ER -

ID: 32177762