Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats

Sanela Smajilovic; Rasmus Schaal-Jensen; Reza Jabbari; Una Smajilovic; Stig Haunso; Jacob Tfelt-Hansen

doi:10.2174/1874192401004010110

Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats

Sanela Smajilovic, Rasmus Schaal-Jensen, Reza Jabbari, Una Smajilovic, Stig Haunso, Jacob Tfelt-Hansen

4 Citationer (Scopus)

Abstract

PTH increases ionic calcium concentration in the serum, acting primarily on bone and kidney cells through the type 1 PTH receptor. Interestingly, PTH stimulates bone formation when administrated intermittently but causes severe bone loss with continuous administration. Daily injections of PTH are used as the most promising anabolic agent in the treatment of severe osteoporosis. Elevated PTH is reported an independent risk factor for left ventricle hypertrophy.

Originalsprog	Engelsk
Tidsskrift	The Open Cardiovascular Medicine Journal
Vol/bind	4
Sider (fra-til)	110-6
Antal sider	7
ISSN	1874-1924
DOI	https://doi.org/10.2174/1874192401004010110
Status	Udgivet - 1 jan. 2010

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10.2174/1874192401004010110

Citationsformater

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title = "Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats",

abstract = "PTH increases ionic calcium concentration in the serum, acting primarily on bone and kidney cells through the type 1 PTH receptor. Interestingly, PTH stimulates bone formation when administrated intermittently but causes severe bone loss with continuous administration. Daily injections of PTH are used as the most promising anabolic agent in the treatment of severe osteoporosis. Elevated PTH is reported an independent risk factor for left ventricle hypertrophy.",

author = "Sanela Smajilovic and Rasmus Schaal-Jensen and Reza Jabbari and Una Smajilovic and Stig Haunso and Jacob Tfelt-Hansen",

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TY - JOUR

T1 - Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats

AU - Smajilovic, Sanela

AU - Schaal-Jensen, Rasmus

AU - Jabbari, Reza

AU - Smajilovic, Una

AU - Haunso, Stig

AU - Tfelt-Hansen, Jacob

PY - 2010/1/1

Y1 - 2010/1/1

N2 - PTH increases ionic calcium concentration in the serum, acting primarily on bone and kidney cells through the type 1 PTH receptor. Interestingly, PTH stimulates bone formation when administrated intermittently but causes severe bone loss with continuous administration. Daily injections of PTH are used as the most promising anabolic agent in the treatment of severe osteoporosis. Elevated PTH is reported an independent risk factor for left ventricle hypertrophy.

AB - PTH increases ionic calcium concentration in the serum, acting primarily on bone and kidney cells through the type 1 PTH receptor. Interestingly, PTH stimulates bone formation when administrated intermittently but causes severe bone loss with continuous administration. Daily injections of PTH are used as the most promising anabolic agent in the treatment of severe osteoporosis. Elevated PTH is reported an independent risk factor for left ventricle hypertrophy.

U2 - 10.2174/1874192401004010110

DO - 10.2174/1874192401004010110

M3 - Journal article

C2 - 20461233

SN - 1874-1924

VL - 4

SP - 110

EP - 116

JO - The Open Cardiovascular Medicine Journal

JF - The Open Cardiovascular Medicine Journal

ER -

Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats

Abstract

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