Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Effect of far infrared therapy on arteriovenous fistula maturation, survival and stenosis in hemodialysis patients, a randomized, controlled clinical trial: the FAITH on fistula trial

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Choice of dialysis modality: patients' experiences and quality of decision after shared decision-making

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Pulmonary artery pressure as a method for assessing hydration status in an anuric hemodialysis patient - a case report

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Cardiac function assessed by myocardial deformation in adult polycystic kidney disease patients

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Diabetes increases the risk of bone fractures in patients on kidney replacement therapy: A DANISH national cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Choice of dialysis modality among patients initiating dialysis: results of the Peridialysis study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Rituximab Treatment in a Patient with Kimura Disease and Membranous Nephropathy: Case Report

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: An arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis treatment. After creation many of the AVFs will never mature or if functioning will need an intervention within 1 year due to an AVF stenosis. Studies investigating possible therapies that improves the AVF maturation and survival are scarce. Far infrared therapy (FIR) has shown promising results. In minor single centre and industry supported trials FIR has shown improved AVF maturation and survival. There is a need of a randomized multicentre controlled trial to examine the effect of FIR on the AVF maturation and survival and to explore the possible AVF protective mechanism induced by the FIR treatment.

METHODS: This investigator initiated, randomized, controlled, open-labeled, multicenter clinical trial will examine the effect of FIR on AVF maturation in patients with a newly created AVF (incident) and AVF patency rate after 1 year of treatment in patients with an existing AVF (prevalent) compared to a control group. The intervention group will receive FIR to the skin above their AVF three times a week for 1 year. The control group will be observed without any treatment. The primary outcome for incident AVFs is the time from surgically creation of the AVF to successful cannulation. The primary outcome for the prevalent AVFs is the difference in number of AVFs without intervention and still functioning in the treatment and control group after 12 months. Furthermore, the acute changes in inflammatory and vasodilating factors during FIR will be explored. Arterial stiffness as a marker of long term AVF patency will also be examined.

DISCUSSION: FIR is a promising new treatment modality that may potentially lead to improved AVF maturation and survival. This randomized controlled open-labelled trial will investigate the effect of FIR and its possible mechanisms.

TRIAL REGISTRATION: Clinicaltrialsgov NCT04011072 (7th of July 2019).

OriginalsprogEngelsk
Artikelnummer283
TidsskriftBMC Nephrology
Vol/bind22
Udgave nummer1
Sider (fra-til)283
ISSN1471-2369
DOI
StatusUdgivet - dec. 2021

ID: 67305925