Effect of carbon dioxide in acute mountain sickness: a rediscovery

T C Harvey, M E Raichle, M H Winterborn, J Jensen, N A Lassen, Norman Richardson, A R Bradwell

35 Citationer (Scopus)

Abstract

The effect of adding CO2 to inhaled air in six subjects with acute mountain sickness was investigated during a medical expedition to 5400 m.3% CO2 in ambient air increased ventilation and resulted in a rise in PaO2 of between 24% and 40%. There was a 9-28% increase in PaCO2 and a reduction of the respiratory alkalosis normally seen at high altitude. Symptoms of acute mountain sickness were rapidly relieved. In three subjects cerebral blood flow increased by 17-39%, so that oxygen delivery to the brain would have been considerably improved. This study confirms earlier suggestions of the beneficial effect of CO2 inhalation at high altitude.
OriginalsprogEngelsk
TidsskriftLancet
Vol/bind2
Udgave nummer8612
Sider (fra-til)639-41
Antal sider3
ISSN0140-6736
StatusUdgivet - 17 sep. 1988

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