Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
E-pub ahead of print

Early Prediction of One-Year Mortality in Ischemic and Haemorrhagic Stroke

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Computer-Based Cognitive Rehabilitation in Patients with Visuospatial Neglect or Homonymous Hemianopia after Stroke

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Social Inequality by Income in Short- and Long-Term Cause-Specific Mortality after Stroke

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Self-Reported Physical Activity and Cardiovascular Disease Risk Factors in Patients with Lacunar Stroke

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Secondary Stroke Prophylaxis with Clopidogrel Produces Sufficient Antiplatelet Response

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Effect of Home-Based High-Intensity Interval Training in Patients With Lacunar Stroke: A Randomized Controlled Trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Forløbsbeskrivelser

    Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiUndervisningpeer review

  3. Neurologiske sygdomme

    Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiUndervisningpeer review

  4. Self-Reported Physical Activity and Cardiovascular Disease Risk Factors in Patients with Lacunar Stroke

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: In Denmark 15%-20% of stroke victims die within the first year. Simple and valid tools are needed to assess patients' risk of dying. The aim of this study was to identify potential predictors of 1-year mortality in stroke victims and construct a simple and valid prediction model.

METHODS: Data were collected retrospectively from a cohort of 1031 stroke victims admitted over a period of 18 months at Nordsjællands Hospital, Denmark. Follow-up was 1 year after symptom onset. Multiple logistic regression analysis with backwards selection was used to identify predictors and construction of a prediction model. The model was validated using cross validation with 10,000 repeated random splits of the dataset. Area under the receiver operating characteristic curve (AUC) and Brier score were used as measures of validity.

RESULTS: Within the first year 186 patients died (18.0%) and 4 (0.4%) were lost to follow-up. Age (OR 1.08), gender (OR 2.19), stroke severity (OR 1.03), Early Warning Score (OR 1.17), Performance Status (ECOG) (OR 1.94), Body Mass Index (OR 0.91), the Charlton's Comorbidity Index (OR 1.17), and urinary problems (OR 2.55) were found to be independent predictors of 1-year mortality. A model including age, stroke severity, Early Warning Score, and Performance Status was found to be valid (AUC 86.5 %, Brier Score 9.03).

CONCLUSIONS: A model including only 4 clinical variables available shortly after admission was able to predict the 1-year mortality risk of patients with acute ischemic and haemorrhagic stroke.

OriginalsprogEngelsk
TidsskriftJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Sider (fra-til)104667
ISSN1052-3057
DOI
StatusE-pub ahead of print - 7 feb. 2020

Bibliografisk note

Copyright © 2020 Elsevier Inc. All rights reserved.

ID: 59291400